Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1535311 | 0.87 | AKR1C3 (0.57) | ALDH1A1MAPTGAAKDM4ELMNA | |
| SCHEMBL7184551 | 0.83 | CDC25B (0.50) | ALDH1A1ALOX15MAPTSMN1; SMN2TSHR | |
| SCHEMBL1081928 | 0.83 | ALDH1A1 (0.59) | ALDH1A1ALOX15MAPTSMN1; SMN2GAA | |
| SCHEMBL7196004 | 0.82 | LIG1 (0.61) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL7188437 | 0.82 | SRD5A2 (0.55) | MAPTGAATP53TSHRKDM4E | |
| SCHEMBL16334491 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL7185592 | 0.82 | MEN1 (0.57) | ALDH1A1ALOX15MAPTSMN1; SMN2GAA | |
| SCHEMBL1718336 | 0.81 | ALDH1A1 (0.40) | ALDH1A1ALOX15MAPTSMN1; SMN2GAA | |
| SCHEMBL12567347 | 0.81 | CA12 (0.41) | ALDH1A1ALOX15MAPTSMN1; SMN2GAA | |
| SCHEMBL10025655 | 0.81 | ALDH1A1 (0.39) | ALDH1A1ALOX15MAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060210452-A1 | Very large scale immobilized polymer synthesis | AFFYMAX TECHNOLOGIES, N.V., A NETHERLANDS ANTILLES CORPORATION | 2006-09-21 | — | — | US | disclosed |
| US-20060194258-A1 | Polypeptide array synthesis | AFFYMETRIX, INC. (US) | 2006-08-31 | — | — | US | disclosed |
| US-7087732-B2 | Nucleotides and analogs having photoremovable protecting groups | AFFYMETRIX, INC. (US) | 2006-08-08 | — | — | US | disclosed |
| US-6955915-B2 | Apparatus comprising polymers | AFFYMETRIX, INC. (US) | 2005-10-18 | — | — | US | disclosed |
| US-20050208537-A1 | Very large scale immobilized polymer synthesis | AFFYMETRIX, INC. (US) | 2005-09-22 | — | — | US | disclosed |
| US-6919211-B1 | Polypeptide arrays | AFFYMETRIX, INC. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20050153362-A1 | Polymer arrays | PIRRUNG MICHAEL C (US) | 2005-07-14 | — | — | US | disclosed |
| US-20050153363-A1 | Polymer arrays | PIRRUNG MICHAEL C (US) | 2005-07-14 | — | — | US | disclosed |
| US-20050118706-A1 | Polymer arrays | AFFYMETRIX, INC. (US) | 2005-06-02 | — | — | US | disclosed |
| US-20050095652-A1 | Apparatus comprising polymers | AFFYMETRIX, INC. (US) | 2005-05-05 | — | — | US | disclosed |
| US-5889165-A | Photolabile nucleoside protecting groups | AFFYMETRIX, INC. (US) | 1999-03-30 | — | — | US | disclosed |
| US-5753788-A | Photolabile nucleoside protecting groups | AFFYMETRIX, INC. (US) | 1998-05-19 | — | — | US | disclosed |
| US-5744101-A | Photolabile nucleoside protecting groups | AFFYMAX TECHNOLOGIES N.V. (GB) | 1998-04-28 | — | — | US | disclosed |
| US-5744305-A | Arrays of materials attached to a substrate | AFFYMETRIX, INC. (US) | 1998-04-28 | — | — | US | disclosed |
| US-5489678-A | 6-NITRO-1,3-BENZOXAZOL-5-YL ALKYLOXY PROTECTIVE GROUP ON THE 5' POSITION OF A DEOXYNUCLEOSIDE; COMPUTERIZED SOLID PHASE SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (NL) | 1996-02-06 | — | — | US | disclosed |
| US-5424186-A | Biosynthesis of oligonucleotides on solid substrate by irradiation of predefined segments to remove blocking agents; then coupling with nucleotide | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-06-13 | — | — | US | disclosed |
| WO-1994010128-A1 | NOVEL PHOTOREACTIVE PROTECTING GROUPS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1994-05-11 | — | — | WO | disclosed |
| EP-0562025-A4 | — | — | 1994-03-30 | — | — | EP | disclosed |
| EP-0562025-A1 | VERY LARGE SCALE IMMOBILIZED POLYMER SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010092-A1 | VERY LARGE SCALE IMMOBILIZED POLYMER SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1992-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194258-A1 | Polypeptide array synthesis | MRPL21, NGLY1, PSAP | ALDH1A1 4233/4885ALOX15 4559/4885MAPT 2780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.