Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001988 | 0.81 | ERN1 (0.48) | ERN1ALDH1A1TSHRCYP1A2ABCG2 | |
| SCHEMBL29459689 | 0.81 | ERN1 (0.48) | ERN1ALDH1A1TSHRCYP1A2ABCG2 | |
| SCHEMBL4039891 | 0.76 | ERN1 (0.44) | ERN1ALDH1A1TSHRCYP1A2ABCG2 | |
| SCHEMBL30681224 | 0.76 | ALDH1A1 (0.48) | ERN1ALDH1A1TSHRCYP1A2ABCG2 | |
| SCHEMBL10923461 | 0.76 | ERN1 (0.53) | ERN1ALDH1A1ABCG2MAPTAOX1 | |
| SCHEMBL4374159 | 0.74 | ERN1 (0.66) | ERN1ALDH1A1TSHRCYP1A2ABCG2 | |
| SCHEMBL453409 | 0.74 | ERN1 (0.43) | ERN1ALDH1A1TSHRCYP1A2ABCG2 | |
| SCHEMBL31663469 | 0.74 | ERN1 (0.66) | ERN1ALDH1A1TSHRCYP1A2ABCG2 | |
| SCHEMBL31813608 | 0.74 | ERN1 (0.43) | ERN1ALDH1A1TSHRCYP1A2ABCG2 | |
| SCHEMBL9246447 | 0.74 | ALDH1A1 (0.43) | ERN1ALDH1A1TSHRCYP1A2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060210452-A1 | Very large scale immobilized polymer synthesis | AFFYMAX TECHNOLOGIES, N.V., A NETHERLANDS ANTILLES CORPORATION | 2006-09-21 | — | — | US | disclosed |
| US-20060194258-A1 | Polypeptide array synthesis | AFFYMETRIX, INC. (US) | 2006-08-31 | — | — | US | disclosed |
| US-7087732-B2 | Nucleotides and analogs having photoremovable protecting groups | AFFYMETRIX, INC. (US) | 2006-08-08 | — | — | US | disclosed |
| US-6955915-B2 | Apparatus comprising polymers | AFFYMETRIX, INC. (US) | 2005-10-18 | — | — | US | disclosed |
| US-20050208537-A1 | Very large scale immobilized polymer synthesis | AFFYMETRIX, INC. (US) | 2005-09-22 | — | — | US | disclosed |
| US-6919211-B1 | Polypeptide arrays | AFFYMETRIX, INC. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20050153362-A1 | Polymer arrays | PIRRUNG MICHAEL C (US) | 2005-07-14 | — | — | US | disclosed |
| US-20050153363-A1 | Polymer arrays | PIRRUNG MICHAEL C (US) | 2005-07-14 | — | — | US | disclosed |
| US-20050118706-A1 | Polymer arrays | AFFYMETRIX, INC. (US) | 2005-06-02 | — | — | US | disclosed |
| US-20050095652-A1 | Apparatus comprising polymers | AFFYMETRIX, INC. (US) | 2005-05-05 | — | — | US | disclosed |
| US-6124102-A | EVALUATING THE BINDING OF COMPOUNDS TO BINDING PROTEINS; INCUBATION OF LABELLED BINDING PROTEIN TO SUBSTRATE, ANALYZE PIXEL INTENSITY AT KNOWN POSITIONS, USE COMPUTER TO ANALYZE RELATIVE BINDING OF COMPOUNDS TO BINDING PROTEIN | AFFYMETRIX, INC. (US) | 2000-09-26 | — | — | US | disclosed |
| US-5889165-A | Photolabile nucleoside protecting groups | AFFYMETRIX, INC. (US) | 1999-03-30 | — | — | US | disclosed |
| US-5753788-A | Photolabile nucleoside protecting groups | AFFYMETRIX, INC. (US) | 1998-05-19 | — | — | US | disclosed |
| US-5744101-A | Photolabile nucleoside protecting groups | AFFYMAX TECHNOLOGIES N.V. (GB) | 1998-04-28 | — | — | US | disclosed |
| US-5744305-A | Arrays of materials attached to a substrate | AFFYMETRIX, INC. (US) | 1998-04-28 | — | — | US | disclosed |
| US-5489678-A | 6-NITRO-1,3-BENZOXAZOL-5-YL ALKYLOXY PROTECTIVE GROUP ON THE 5' POSITION OF A DEOXYNUCLEOSIDE; COMPUTERIZED SOLID PHASE SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (NL) | 1996-02-06 | — | — | US | disclosed |
| US-5424186-A | Biosynthesis of oligonucleotides on solid substrate by irradiation of predefined segments to remove blocking agents; then coupling with nucleotide | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-06-13 | — | — | US | disclosed |
| EP-0562025-A4 | — | — | 1994-03-30 | — | — | EP | disclosed |
| EP-0562025-A1 | VERY LARGE SCALE IMMOBILIZED POLYMER SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010092-A1 | VERY LARGE SCALE IMMOBILIZED POLYMER SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1992-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194258-A1 | Polypeptide array synthesis | MRPL21, NGLY1, PSAP | ERN1 881/4885ALDH1A1 4233/4885TSHR 2311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.