Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | APLNR | P35414 | 1/20 | 0.59 |
| ▸ | GLP1R | P43220 | 1/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.59 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.59 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2862015 | 0.99 | NPSR1 (0.63) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| SCHEMBL2865254 | 0.88 | NPSR1 (0.64) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| SCHEMBL2861923 | 0.85 | NPSR1 (0.61) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| SCHEMBL2861556 | 0.84 | NPSR1 (0.61) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| Hydrochloric Acid SCHEMBL2865785 | 0.83 | NPSR1 (0.58) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| SCHEMBL2870919 | 0.83 | NPSR1 (0.63) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| SCHEMBL2868953 | 0.82 | NPSR1 (0.57) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| SCHEMBL2861708 | 0.82 | NPSR1 (0.72) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| Hydrochloric Acid SCHEMBL2868925 | 0.81 | NPSR1 (0.60) | NPSR1ADRB2APLNRGLP1RFFAR4 | |
| Hydrochloric Acid SCHEMBL2858769 | 0.81 | NPSR1 (0.57) | NPSR1ADRB2APLNRGLP1RFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661898-A1 | BICYCLIC PIPERAZINE COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2006-05-31 | — | — | EP | disclosed |