Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115482 | 0.77 | MAPT (0.42) | ALDH1A1L3MBTL1KDM4EMAPT | |
| SCHEMBL24524714 | 0.75 | MAPT (0.40) | ALDH1A1L3MBTL1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL31612219 | 0.75 | MAPT (0.40) | ALDH1A1L3MBTL1KDM4EMAPT | |
| Boric Acid SCHEMBL28562706 | 0.70 | MAPT (0.36) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL7927935 | 0.70 | MAPT (0.36) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL2575881 | 0.69 | — | — | |
| SCHEMBL23339267 | 0.69 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL7930524 | 0.69 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL6764110 | 0.68 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL3513091 | 0.67 | MAPT (0.36) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038001-A1 | AMINOPYRIMIDINE DERIVATIVES AS JNK INHIBITORS | CELLTECH R & D LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |