Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6039630 | 0.79 | CTSK (0.37) | CTSKCTSDCTSLCTSBCTSS | |
| SCHEMBL9988140 | 0.74 | HPGD (0.35) | CTSKCTSDCTSLCTSBCTSS | |
| SCHEMBL10339672 | 0.71 | HDAC6 (0.37) | CTSKCTSDCTSLCTSBCTSS | |
| SCHEMBL27616273 | 0.70 | CTSK (0.38) | CTSKCTSDCTSLCTSBCTSS | |
| SCHEMBL6039837 | 0.70 | HPGD (0.36) | CTSKCTSDCTSLCTSBCTSS | |
| SCHEMBL4669410 | 0.70 | HDAC6 (0.36) | CTSDCTSLCTSBCTSSHDAC1 | |
| Hydrochloric Acid SCHEMBL27695054 | 0.69 | CTSK (0.37) | CTSKCTSDCTSLCTSBCTSS | |
| SCHEMBL7712884 | 0.69 | AKT1 (0.44) | CTSLCTSBCTSSHDAC1HDAC2 | |
| SCHEMBL1027506 | 0.68 | HPGD (0.37) | CTSKCTSDCTSLCTSBCTSS | |
| SCHEMBL7747843 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038001-A1 | AMINOPYRIMIDINE DERIVATIVES AS JNK INHIBITORS | CELLTECH R & D LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |