Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27763214 | 0.97 | HSD17B10 (0.36) | HSD17B10MEN1KMT2AFDPSALDH1A1 | |
| SCHEMBL7139126 | 0.97 | — | — | |
| SCHEMBL1177685 | 0.80 | HSD17B10 (0.32) | HSD17B10HTTMAPT | |
| SCHEMBL3149716 | 0.77 | — | — | |
| SCHEMBL10588321 | 0.70 | — | — | |
| SCHEMBL27462201 | 0.69 | TSHR (0.39) | MAPT | |
| SCHEMBL10149589 | 0.63 | NPC1 (0.32) | ALDH1A1MAPT | |
| SCHEMBL28351367 | 0.63 | NPC1 (0.32) | ALDH1A1MAPT | |
| SCHEMBL6624504 | 0.63 | — | — | |
| N-Methylpiperidine SCHEMBL29091220 | 0.63 | LMNA (0.38) | MEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328000-A2 | Indolocarbazole derivatives, process for their preparation and medicines containing same | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1989-08-16 | — | — | EP | claimed |
| WO-2006038001-A1 | AMINOPYRIMIDINE DERIVATIVES AS JNK INHIBITORS | CELLTECH R & D LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |
| EP-1474420-A1 | QUINAZOLINE COMPOUNDS | Astrazeneca AB (SE) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003064413-A1 | QUINAZOLINE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-07 | — | — | WO | disclosed |
| EP-1309587-A1 | CINNOLINE COMPOUNDS | AstraZeneca AB (SE) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002016348-A1 | ANTIANGIOGENIC BICYCLIC DERIVATIVES | ASTRAZENECA AB (SE) | 2002-02-28 | — | — | WO | disclosed |
| WO-2002012228-A1 | CINNOLINE COMPOUNDS | ASTRAZENECA AB (SE) | 2002-02-14 | — | — | WO | disclosed |
| EP-0328000-A2 | Indolocarbazole derivatives, process for their preparation and medicines containing same | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1989-08-16 | — | — | EP | disclosed |