Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 6/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4445476 | 0.79 | — | — | |
| SCHEMBL1462497 | 0.78 | TSHR (0.57) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL1740597 | 0.78 | TSHR (0.57) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL27350082 | 0.76 | SAT1 (0.52) | TDP1LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL28380870 | 0.76 | SAT1 (0.52) | TDP1LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL9801336 | 0.76 | CA2 (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9801340 | 0.76 | CA2 (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9801062 | 0.76 | CA2 (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9801491 | 0.76 | CA2 (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9801897 | 0.76 | CA2 (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038001-A1 | AMINOPYRIMIDINE DERIVATIVES AS JNK INHIBITORS | CELLTECH R & D LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |