Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.79 |
| ▸ | MAOA | P21397 | 2/20 | 0.79 |
| ▸ | F10 | P00742 | 14/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | CALML3 | P27482 | 1/20 | 0.64 |
| ▸ | SDHA | P31040 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846255 | 0.90 | MAOB (0.82) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL27552994 | 0.90 | MAOB (0.79) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL5216684 | 0.89 | MAOB (0.84) | MAOBMAOAF10LMNAPTGS1 | |
| Sutezolid SCHEMBL2152517 | 0.89 | MAOB (1.00) | MAOBMAOAF10LMNAPTGS1 | |
| Sutezolid SCHEMBL29757643 | 0.89 | MAOB (1.00) | MAOBMAOAF10LMNAPTGS1 | |
| Sutezolid SCHEMBL2152519 | 0.89 | MAOB (1.00) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL7156352 | 0.87 | MAOA (0.60) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL7704129 | 0.87 | MAOB (0.61) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL18410470 | 0.87 | MAOB (0.81) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL18408828 | 0.87 | MAOB (0.82) | MAOBMAOAF10LMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049443-B2 | Amide-containing compound having improved solubility and method of improving the solubility of an amide-containing compound | PHARMACIA & UPJOHN COMPANY (US) | 2006-05-23 | — | — | US | disclosed |