Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 9/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 9/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 9/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1798143 | 0.88 | CSNK2A2 (0.47) | MAPK14MAPK13MAPK12MAPK11SMN1; SMN2 | |
| SCHEMBL31482264 | 0.78 | HDAC3 (0.50) | MAPK14MAPK13MAPK12MAPK11KMT2A | |
| SCHEMBL2664708 | 0.77 | CSNK2A2 (0.51) | MAPTKDM4ECSNK2A2CSNK2A1 | |
| SCHEMBL2664704 | 0.75 | SCD (0.52) | CSNK2A2CSNK2A1 | |
| SCHEMBL14018652 | 0.75 | SMN1; SMN2 (0.45) | KMT2AMEN1RAB9ASMN1; SMN2GFER | |
| SCHEMBL2664705 | 0.73 | CSNK2A2 (0.47) | CSNK2A2CSNK2A1 | |
| SCHEMBL2666371 | 0.71 | MAOB (0.41) | KMT2AMEN1RAB9ASMN1; SMN2GFER | |
| SCHEMBL2664709 | 0.68 | GCK (0.49) | CSNK2A2CSNK2A1 | |
| SCHEMBL4252563 | 0.68 | MAPK14 (0.74) | MAPK14MAPK13MAPK12MAPK11KMT2A | |
| SCHEMBL9071499 | 0.67 | SMN1; SMN2 (0.40) | RAB9ASMN1; SMN2POLBGFERNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420784-B1 | COMPOUNDS EFFECTING GLUCOKINASE | ASTRAZENECA AB (SE) | 2006-04-19 | — | — | EP | disclosed |