SCHEMBL6041052

SCHEMBL6041052

NSP(=O)(SN)n1ccc2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.40
CDK4 P11802 4/20 0.38
CCND1 P24385 4/20 0.38
NOTUM Q6P988 1/20 0.38
LMNA P02545 2/20 0.37
HTR6 P50406 3/20 0.36
TSHR P16473 2/20 0.36
RAB9A P51151 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PRKD3 O94806 1/20 0.36
PRKCG P05129 1/20 0.36
PRKCB P05771 1/20 0.36
PRKCA P17252 1/20 0.36
PRKACA P17612 1/20 0.36
PRKACG P22612 1/20 0.36
PRKACB P22694 1/20 0.36
PRKCH P24723 1/20 0.36
PRKCI P41743 1/20 0.36
PRKCE Q02156 1/20 0.36
PRKCQ Q04759 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6041081 0.79 CDK4 (0.42) KMT2ACDK4CCND1NOTUMLMNA
SCHEMBL21806773 0.79 NOTUM (0.46) KMT2ACDK4CCND1NOTUMLMNA
SCHEMBL14076797 0.73 CDK4 (0.41) KMT2ACDK4CCND1NOTUMLMNA
SCHEMBL30037074 0.72 KMT2A (0.44) KMT2ACDK4CCND1NOTUMLMNA
SCHEMBL6041051 0.71 CDK4 (0.42) KMT2ACDK4CCND1NOTUMLMNA
SCHEMBL22393392 0.70 NOTUM (0.42) KMT2ACDK4CCND1NOTUMLMNA
SCHEMBL6048112 0.68 FDPS (0.42) LMNATSHRALDH1A1HTTROCK1
SCHEMBL28895756 0.67 NOTUM (0.39) KMT2ACDK4CCND1NOTUMLMNA
SCHEMBL29530903 0.66 CDK4 (0.50) KMT2ACDK4CCND1NOTUMLMNA
SCHEMBL5334126 0.66 CDK4 (0.50) KMT2ACDK4CCND1NOTUMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1632253-A1 Material for odour control BKI Holding Corporation (US) 2006-03-08 EP disclosed
WO-2006017441-A1 MATERIAL FOR ODOR CONTROL BKI HOLDING CORPORATION (US) 2006-02-16 WO disclosed
US-20060029567-A1 Material for odor control BKI HOLDING CORPORATION (US) 2006-02-09 US disclosed
US-4530714-A Capable of forming urea under use conditions ALLIED CORPORATION (US) 1985-07-23 US disclosed
EP-0119487-A1 Novel N-aliphatic and N,N-aliphatic phosphoric triamide urease inhibitors and urease inhibited urea based fertilizer compositions ALLIED CORPORATION (US) 1984-09-26 EP disclosed