SCHEMBL6041158

SCHEMBL6041158

CCC[SiH](OCC1CO1)O[Si](OCC)(OCC)OCC

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6770126 0.86 SMN1; SMN2 (0.36) SMN1; SMN2ALDH1A1TDP1
SCHEMBL7919984 0.83 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1TDP1
SCHEMBL1564891 0.80 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1TDP1
SCHEMBL1565347 0.76 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1TDP1
SCHEMBL11624164 0.75 SMN1; SMN2 (0.44) SMN1; SMN2ALDH1A1TDP1
SCHEMBL4950712 0.72 SMN1; SMN2 (0.38) SMN1; SMN2ALDH1A1TDP1
SCHEMBL9819422 0.72 SMN1; SMN2 (0.44) SMN1; SMN2ALDH1A1TDP1
SCHEMBL4357523 0.72 SMN1; SMN2 (0.35) SMN1; SMN2ALDH1A1TDP1
SCHEMBL3856312 0.72 SMN1; SMN2 (0.42) SMN1; SMN2ALDH1A1TDP1
SCHEMBL10727678 0.71 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10414902-B2 Anti-corrosive coating compound EWALD DÖRKEN AG (DE) 2019-09-17 US disclosed
EP-2980166-B1 Anticorrosive coating composition DOERKEN EWALD AG (DE) 2017-06-07 EP disclosed
US-20160032110-A1 ANTI-CORROSIVE COATING COMPOUND EWALD DOERKEN AG (DE) 2016-02-04 US disclosed
EP-2980166-A1 Anticorrosive coating composition EWALD DÖRKEN AG (DE) 2016-02-03 EP disclosed
US-9023316-B2 Synthesis of 18F-labeled tracers in hydrous organic solvents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2015-05-05 US disclosed
EP-1147222-B1 REPLICABLE PROBE ARRAY SURMODICS INC (US) 2006-11-22 EP disclosed
EP-1349956-A2 REPLICABLE PROBE ARRAY SurModics, Inc. (US) 2003-10-08 EP disclosed
US-20030170914-A1 Replicable probe array SURMODICS, INC 2003-09-11 US disclosed
US-20030148360-A1 Replicable probe array SURMODICS, INC. (US) 2003-08-07 US disclosed
US-6514768-B1 Immobilization of specific binding ligands (nucleic acids) and other ligands in known spatial arrangement; microarrays; photoreactive groups; reusable SURMODICS, INC. 2003-02-04 US disclosed
WO-2002010450-A2 REPLICABLE PROBE ARRAY SURMODICS, INC. (US) 2002-02-07 WO disclosed
EP-1147222-A1 REPLICABLE PROBE ARRAY SurModics, Inc. (US) 2001-10-24 EP disclosed
WO-2000044939-A1 REPLICABLE PROBE ARRAY SURMODICS, INC. (US) 2000-08-03 WO disclosed