Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770126 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL6041158 | 0.83 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL1565347 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL1564891 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL11624164 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL4950712 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL10727678 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL28432639 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL4357523 | 0.73 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL9819422 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6181517-B1 | Magnetic disc drive system with liquid film lubricating agent | NEC CORPORATION (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-0577789-A1 | ELECTRORHEOLOGICAL FLUIDS CONTAINING CELLULOSE AND FUNCTIONALIZED POLYSILOXANES | The Lubrizol Corporation (US) | 1994-01-12 | — | — | EP | disclosed |
| WO-1993014180-A1 | ELECTRORHEOLOGICAL FLUIDS CONTAINING CELLULOSE AND FUNCTIONALIZED POLYSILOXANES | THE LUBRIZOL CORPORATION (US) | 1993-07-22 | — | — | WO | disclosed |