Quercetin

Quercetin

SCHEMBL6042686

O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12.O=c1c(O)c(-c2ccc(O)c(O)c2O)oc2ccccc12

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 12/20 0.71
KMT2A Q03164 12/20 0.71
CYP3A4 P08684 9/20 0.71
KDM4E B2RXH2 9/20 0.71
HSD17B10 Q99714 9/20 0.71
MAPT P10636 9/20 0.71
CYP2C9 P11712 8/20 0.71
RECQL P46063 8/20 0.71
ALOX15 P16050 7/20 0.71
CYP1A2 P05177 7/20 0.71
XDH P47989 7/20 0.71
APP P05067 7/20 0.71
TP53 P04637 6/20 0.71
FTO Q9C0B1 6/20 0.71
CYP1A1 P04798 6/20 0.71
CYP1B1 Q16678 6/20 0.71
CYP2D6 P10635 5/20 0.71
CYP2C19 P33261 5/20 0.71
GAA P10253 5/20 0.71
POLB P06746 5/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Kaempferol SCHEMBL731179 0.93 MEN1 (0.68) MEN1KMT2ACYP3A4KDM4EHSD17B10
Quercetin SCHEMBL111510 0.90 MEN1 (0.76) MEN1KMT2ACYP3A4KDM4EHSD17B10
Quercetin SCHEMBL729498 0.90 MEN1 (0.76) MEN1KMT2ACYP3A4KDM4EHSD17B10
Morin SCHEMBL8740028 0.85 MEN1 (0.77) MEN1KMT2ACYP3A4KDM4EHSD17B10
Quercetin SCHEMBL29353785 0.84 MEN1 (1.00) MEN1KMT2ACYP3A4KDM4EHSD17B10
Quercetin SCHEMBL17629824 0.84 MEN1 (1.00) MEN1KMT2ACYP3A4KDM4EHSD17B10
Quercetin SCHEMBL29723041 0.84 MEN1 (1.00) MEN1KMT2ACYP3A4KDM4EHSD17B10
Quercetin SCHEMBL19723 0.84 MEN1 (1.00) MEN1KMT2ACYP3A4KDM4EHSD17B10
Quercetin SCHEMBL29351036 0.84 MEN1 (1.00) MEN1KMT2ACYP3A4KDM4EHSD17B10
Quercetin SCHEMBL118425 0.84 MEN1 (1.00) MEN1KMT2ACYP3A4KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060084135-A1 Compositions for manipulating the lifespan and stress response of cells and organisms BIOMOL INTERNATIONAL, INC. 2006-04-20 US disclosed