⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6989690 | 0.98 | — | — | |
| SCHEMBL9236740 | 0.81 | — | — | |
| SCHEMBL2633817 | 0.79 | — | — | |
| SCHEMBL2487767 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL9098881 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL424014 | 0.78 | HTT (0.33) | — | |
| Hydrochloric Acid SCHEMBL2693228 | 0.78 | HTT (0.33) | — | |
| SCHEMBL6447288 | 0.77 | — | — | |
| SCHEMBL6602444 | 0.74 | — | — | |
| Imidazole Acetic Acid SCHEMBL9099789 | 0.72 | GABRR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250114380-A1 | SMALL MOLECULE CD38 INHIBITORS AND METHODS OF USING SAME | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2025-04-10 | — | — | US | disclosed |
| US-20060084135-A1 | Compositions for manipulating the lifespan and stress response of cells and organisms | BIOMOL INTERNATIONAL, INC. | 2006-04-20 | — | — | US | disclosed |
| CN-1087635-A | Novel thiazole derivative, its preparation method and medical composition thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1994-06-08 | — | — | CN | disclosed |
| EP-0397365-B1 | Arylthiazolylimidazoles as 5HT3 Antagonists | PFIZER (US) | 1994-03-02 | — | — | EP | disclosed |
| EP-0397365-A1 | Arylthiazolylimidazoles as 5HT3 Antagonists | PFIZER INC. (US) | 1990-11-14 | — | — | EP | disclosed |
| US-4914207-A | ANTIEMETICS | PFIZER INC. (US) | 1990-04-03 | — | — | US | disclosed |