⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole Acetic Acid SCHEMBL9099789 | 0.83 | GABRR1 (0.41) | — | |
| Imidazole Acetic Acid SCHEMBL637983 | 0.83 | — | — | |
| Imidazole Acetic Acid SCHEMBL27340954 | 0.83 | — | — | |
| Imidazole Acetic Acid SCHEMBL45374 | 0.81 | ALDH1A1 (0.41) | — | |
| SCHEMBL4434828 | 0.81 | — | — | |
| Imidazole Acetic Acid SCHEMBL2787422 | 0.81 | GABRR1 (0.40) | — | |
| SCHEMBL9238935 | 0.81 | — | — | |
| SCHEMBL1286676 | 0.81 | — | — | |
| Imidazole Acetic Acid SCHEMBL28497348 | 0.81 | ALDH1A1 (0.41) | — | |
| Imidazole Acetic Acid SCHEMBL27315430 | 0.81 | GABRR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050130941-A1 | Methods of treating alzheimer's disease | PHARMACIA & UPJOHN COMPANY LLC | 2005-06-16 | — | — | US | disclosed |
| EP-1392315-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100410-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| US-5753652-A | Antiretroviral hydrazine derivatives | NOVARTIS CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0604368-B1 | Anti retroviral hydrazine derivatives | CIBA GEIGY AG (CH) | 1996-09-18 | — | — | EP | disclosed |
| CN-1093701-A | Antiretroviral hydrazine derivative | CIBA GEIGY AG (CH) | 1994-10-19 | — | — | CN | disclosed |
| EP-0604368-A1 | Anti retroviral hydrazine derivatives | CIBA-GEIGY AG (CH) | 1994-06-29 | — | — | EP | disclosed |