Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016954 | 0.81 | GABRA1 (0.48) | GABRA1GABRB2IDO1TAAR1LMNA | |
| SCHEMBL622471 | 0.79 | — | — | |
| SCHEMBL29562705 | 0.77 | GABRA1 (0.44) | GABRA1GABRB2IDO1TAAR1LMNA | |
| SCHEMBL305224 | 0.77 | GABRA1 (0.44) | GABRA1GABRB2IDO1TAAR1LMNA | |
| SCHEMBL28958233 | 0.75 | TAAR1 (0.48) | GABRA1GABRB2IDO1TAAR1 | |
| SCHEMBL4449960 | 0.75 | GABRA1 (0.48) | GABRA1GABRB2IDO1TAAR1TSHR | |
| SCHEMBL608328 | 0.75 | GABRA1 (0.42) | GABRA1GABRB2IDO1TAAR1LMNA | |
| SCHEMBL4896383 | 0.75 | GABRA1 (0.42) | GABRA1GABRB2IDO1TAAR1LMNA | |
| SCHEMBL11104057 | 0.75 | GABRA1 (0.48) | GABRA1GABRB2IDO1TAAR1LMNA | |
| SCHEMBL31192635 | 0.75 | GABRA1 (0.42) | GABRA1GABRB2IDO1TAAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060084135-A1 | Compositions for manipulating the lifespan and stress response of cells and organisms | BIOMOL INTERNATIONAL, INC. | 2006-04-20 | — | — | US | disclosed |
| US-4728646-A | ANTITHROMBOTICS | DR. KARL THOMAE GMBH (DE) | 1988-03-01 | — | — | US | disclosed |
| US-4690923-A | ANTITHROMBOTICS | KARL THOMAE GMBH (DE) | 1987-09-01 | — | — | US | disclosed |
| US-4518596-A | Antithrombotic use of 2-(perhydro-1,4-diazino)-pyrimido (5,4,D)-pyrimidines | DR. KARL THOMAE GMBH (DE) | 1985-05-21 | — | — | US | disclosed |