⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399664 | 0.89 | — | — | |
| SCHEMBL9979497 | 0.80 | — | — | |
| SCHEMBL8080704 | 0.77 | LMNA (0.32) | — | |
| SCHEMBL10400018 | 0.74 | — | — | |
| SCHEMBL7743500 | 0.71 | — | — | |
| SCHEMBL3231790 | 0.71 | LMNA (0.42) | — | |
| SCHEMBL6285511 | 0.71 | LMNA (0.42) | — | |
| SCHEMBL3233600 | 0.71 | LMNA (0.42) | — | |
| SCHEMBL20684797 | 0.71 | — | — | |
| SCHEMBL294253 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107840825-B | Hepta-fluoroiso-propyl quinolines and the preparation method and application thereof | 湖南化工研究院有限公司 | 2019-11-05 | — | — | CN | disclosed |
| US-20060122240-A1 | Benzotriazoles and methods of prophylaxis or treatment of metabolic-related disorders thereof | ARENA PHARMACEUTICALS, INC. (US) | 2006-06-08 | — | — | US | disclosed |
| US-6919291-B2 | Fluorinated zwitterionic cocatalyst activators for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20040110631-A1 | Fluorinated zwitterionic cocatalyst activators for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-06-10 | — | — | US | disclosed |
| WO-2004041274-A1 | BENZOTRIAZOLES AND METHODS OF PROPHYLAXIS OR TREATMENT OF METABOLIC-RELATED DISORDERS THEREOF | ARENA PHARMACEUTICALS, INC. (US) | 2004-05-21 | — | — | WO | disclosed |
| EP-1349653-A2 | FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION | ExxonMobil Chemical Patents Inc. (US) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002036639-A2 | FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2002-05-10 | — | — | WO | disclosed |
| US-3965074-A | Homopolymers of polyfluorinated vinyl isocyanates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-06-22 | — | — | US | disclosed |
| US-3943112-A | PERFLUORINATED VINYL ISOCYANATE COPOLYMERS; OIL AND WATER REPELLENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-03-09 | — | — | US | disclosed |