SCHEMBL6044972

SCHEMBL6044972

CCOC(=O)C(=CO)CC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.45
GLO1 Q04760 1/20 0.45
SOAT1 P35610 1/20 0.44
ALDH1A1 P00352 5/20 0.42
LMNA P02545 3/20 0.40
HSD17B10 Q99714 1/20 0.40
CYP2D6 P10635 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TSHR P16473 1/20 0.39
ALOX15 P16050 1/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
EGLN1 Q9GZT9 1/20 0.38
CYP2C9 P11712 2/20 0.37
HCAR2 Q8TDS4 1/20 0.37
MAPT P10636 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9889451 1.00 NPSR1 (0.45) NPSR1GLO1SOAT1ALDH1A1LMNA
SCHEMBL12317093 1.00 NPSR1 (0.45) NPSR1GLO1SOAT1ALDH1A1LMNA
SCHEMBL22472115 0.84 NPSR1 (0.43) NPSR1GLO1SOAT1ALDH1A1LMNA
SCHEMBL7601504 0.83 NPSR1 (0.46) NPSR1GLO1SOAT1ALDH1A1LMNA
SCHEMBL7600152 0.83 NPSR1 (0.46) NPSR1GLO1SOAT1ALDH1A1LMNA
SCHEMBL23094584 0.80 GAA (0.56) NPSR1GLO1ALDH1A1LMNAHSD17B10
SCHEMBL8321920 0.80 GAA (0.56) NPSR1GLO1ALDH1A1LMNAHSD17B10
SCHEMBL8009911 0.80 NPSR1 (0.41) NPSR1GLO1SOAT1ALDH1A1LMNA
SCHEMBL3356854 0.79 NPSR1 (0.43) NPSR1GLO1SOAT1ALDH1A1LMNA
SCHEMBL5144385 0.79 NPSR1 (0.43) NPSR1GLO1SOAT1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1694302-A1 TASTE MASKED PHARMACEUTICAL COMPOSITIONS COMPRISING BITTER DRUG AND pH SENSITIVE POLYMER Council of Scientific and Industrial Research (IN) 2006-08-30 EP claimed
WO-2005055987-A1 TASTE MASKED PHARMACEUTICAL COMPOSITIONS COMPRISING BITTER DRUG AND pH SENSITIVE POLYMER COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2005-06-23 WO claimed
US-20050136114-A1 Taste masked pharmaceutical compositions comprising bitter drug and pH sensitive polymer COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-06-23 US claimed
CN-116715953-B Antistatic self-repairing polyurethane material suitable for marine environment and preparation method and application thereof 中裕软管科技股份有限公司 2023-10-24 CN disclosed
CN-116715953-A Antistatic self-repairing polyurethane material suitable for marine environment and preparation method and application thereof 中裕软管科技股份有限公司 2023-09-08 CN disclosed
CN-109616468-A Lighting module LG伊诺特有限公司 2019-04-12 CN disclosed
CN-103347864-B Pyrimidone compounds for use in the treatment of diseases or conditions mediated by Lp-PLA 2 葛兰素集团有限公司 2016-08-10 CN disclosed
CN-104478812-A Pyrimidone compound for treating Lp-PLA2-mediated diseases or illness GLAXO GROUP LTD 2015-04-01 CN disclosed
EP-1694302-A1 TASTE MASKED PHARMACEUTICAL COMPOSITIONS COMPRISING BITTER DRUG AND pH SENSITIVE POLYMER Council of Scientific and Industrial Research (IN) 2006-08-30 EP disclosed
WO-2005055987-A1 TASTE MASKED PHARMACEUTICAL COMPOSITIONS COMPRISING BITTER DRUG AND pH SENSITIVE POLYMER COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2005-06-23 WO disclosed
US-20050136114-A1 Taste masked pharmaceutical compositions comprising bitter drug and pH sensitive polymer COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-06-23 US disclosed
US-4617405-A REACTING ACID ANHYDRIDE WITH BETA-HYDROXY CARBONYL COMPOUND AND TREATING ESTER FORMED WITH BASIC CATALYST A. E. STALEY MANUFACTURING COMPANY (US) 1986-10-14 US disclosed