SCHEMBL6045291

SCHEMBL6045291

CC(CC(O)C(N)CC(Cc1ccc(C(C)(C)C)c(OC[C@@H](O)CCl)c1)C(C)C)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6044119 1.00 REN (0.59) REN
SCHEMBL6044115 1.00 REN (0.59) REN
SCHEMBL6045287 1.00 REN (0.59) REN
SCHEMBL6044108 1.00 REN (0.59) REN
SCHEMBL6044573 0.90 REN (0.59) REN
SCHEMBL6044560 0.90 REN (0.59) REN
SCHEMBL6044564 0.90 REN (0.59) REN
SCHEMBL6044637 0.89 REN (0.62) REN
SCHEMBL6044644 0.89 REN (0.62) REN
SCHEMBL6044640 0.89 REN (0.62) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060154926-A1 Methods of treating alzheimer's disease using aryl alkanoic acid amides ELAN PHARMACEUTICALS, INC. 2006-07-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060154926-A1 Methods of treating alzheimer's disease using aryl alkanoic acid amides BACE1, APP, PSEN1 REN 970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.