Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6045621 | 0.90 | OPRM1 (0.49) | OPRM1OPRD1OPRK1CHRM2CHRM3 | |
| SCHEMBL6045500 | 0.89 | OPRM1 (0.69) | OPRM1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2990423 | 0.89 | OPRM1 (0.58) | OPRM1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6045487 | 0.89 | OPRM1 (0.58) | OPRM1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| Oxalic Acid SCHEMBL6045792 | 0.88 | OPRM1 (0.48) | OPRM1OPRD1OPRK1KDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL6045513 | 0.87 | OPRM1 (0.56) | OPRM1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| Oxalic Acid SCHEMBL6045761 | 0.87 | OPRM1 (0.67) | OPRM1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9233522 | 0.87 | CYP3A4 (0.56) | OPRM1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9232318 | 0.87 | CYP3A4 (0.56) | OPRM1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6045543 | 0.85 | OPRM1 (0.56) | OPRM1CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252797-A1 | Receptor regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-11-09 | — | — | US | disclosed |
| EP-1559428-A1 | RECEPTOR REGULATOR | Takeda Pharmaceutical Company Limited (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252797-A1 | Receptor regulator | NMUR1, NMUR2, NMBR | OPRM1 148/4885CYP3A4 4753/4885CYP2D6 4634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.