⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28221053 | 0.57 | — | — | |
| SCHEMBL7631489 | 0.53 | — | — | |
| SCHEMBL9436725 | 0.50 | — | — | |
| SCHEMBL3628796 | 0.43 | LMNA (0.30) | — | |
| Scyllitol SCHEMBL4447990 | 0.41 | LMNA (1.00) | — | |
| Scyllitol SCHEMBL959405 | 0.41 | LMNA (1.00) | — | |
| Scyllitol SCHEMBL188237 | 0.41 | LMNA (1.00) | — | |
| Scyllitol SCHEMBL188106 | 0.41 | LMNA (1.00) | — | |
| Scyllitol SCHEMBL5969 | 0.41 | LMNA (1.00) | — | |
| Scyllitol SCHEMBL12377889 | 0.41 | LMNA (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3405455-B1 | 2-OXINDOLE COMPOUNDS | CHEMOCENTRYX INC (US) | 2024-02-28 | — | — | EP | disclosed |
| US-20060252797-A1 | Receptor regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-11-09 | — | — | US | disclosed |
| EP-1559428-A1 | RECEPTOR REGULATOR | Takeda Pharmaceutical Company Limited (JP) | 2005-08-03 | — | — | EP | disclosed |