Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 9/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6045761 | 0.94 | OPRM1 (0.67) | OPRM1OPRD1OPRK1LMNACACNA1C | |
| Oxalic Acid SCHEMBL6045521 | 0.93 | OPRM1 (0.61) | OPRM1OPRD1MEN1KMT2AALDH1A1 | |
| SCHEMBL6045500 | 0.92 | OPRM1 (0.69) | OPRM1OPRD1OPRK1LMNACACNA1C | |
| Oxalic Acid SCHEMBL6045695 | 0.89 | OPRM1 (0.57) | OPRM1OPRD1MEN1KMT2AALDH1A1 | |
| Fumaric Acid SCHEMBL6045658 | 0.87 | OPRM1 (0.63) | OPRM1OPRD1OPRK1LMNACACNA1C | |
| Maleic Acid SCHEMBL6045651 | 0.87 | OPRM1 (0.63) | OPRM1OPRD1OPRK1LMNACACNA1C | |
| Oxalic Acid SCHEMBL6045786 | 0.86 | OPRM1 (0.58) | OPRM1OPRD1MEN1KMT2AALDH1A1 | |
| Oxalic Acid SCHEMBL6045680 | 0.86 | OPRM1 (0.52) | OPRM1OPRD1MEN1KMT2AALDH1A1 | |
| Oxalic Acid SCHEMBL6045583 | 0.86 | OPRM1 (0.56) | OPRM1OPRD1MEN1KMT2AALDH1A1 | |
| Oxalic Acid SCHEMBL6045513 | 0.85 | OPRM1 (0.56) | OPRM1OPRD1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252797-A1 | Receptor regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-11-09 | — | — | US | disclosed |
| EP-1559428-A1 | RECEPTOR REGULATOR | Takeda Pharmaceutical Company Limited (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252797-A1 | Receptor regulator | NMUR1, NMUR2, NMBR | OPRM1 148/4885OPRD1 180/4885MEN1 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.