Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9376659 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2OPRM1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL25389653 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2OPRM1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL2985757 | 0.82 | SMN1; SMN2 (0.75) | SMN1; SMN2OPRM1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL7706443 | 0.82 | SMN1; SMN2 (0.63) | SMN1; SMN2OPRM1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL15026729 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2OPRM1RECQLALDH1A1TSHR | |
| SCHEMBL5242605 | 0.81 | OPRM1 (0.60) | SMN1; SMN2OPRM1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL16876702 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2OPRM1CYP3A4HSD17B10POLB | |
| SCHEMBL7705959 | 0.79 | SMN1; SMN2 (0.59) | SMN1; SMN2OPRM1ALDH1A1POLBLMNA | |
| SCHEMBL16876738 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2OPRM1CYP3A4HSD17B10POLB | |
| SCHEMBL15461526 | 0.79 | CYP2D6 (0.59) | SMN1; SMN2OPRM1ALDH1A1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252797-A1 | Receptor regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-11-09 | — | — | US | disclosed |
| EP-1559428-A1 | RECEPTOR REGULATOR | Takeda Pharmaceutical Company Limited (JP) | 2005-08-03 | — | — | EP | disclosed |
| EP-0921125-B1 | 1,3,8-Triazaspiro[4,5]decan-4-on derivatives | HOFFMANN LA ROCHE (CH) | 2002-01-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252797-A1 | Receptor regulator | NMUR1, NMUR2, NMBR | SMN1; SMN2 2715/4885OPRM1 148/4885RECQL 3389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.