Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 7/20 | 0.49 |
| ▸ | CA9 | Q16790 | 7/20 | 0.49 |
| ▸ | FABP3 | P05413 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118459 | 0.81 | CA1 (0.62) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9135099 | 0.81 | CA1 (0.62) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL10860884 | 0.80 | TSHR (0.43) | CA1CA2MMP1MMP2MMP9 | |
| Phthalic Acid SCHEMBL28209794 | 0.79 | ALDH1A1 (0.61) | CA1CA2MMP1MMP2MMP9 | |
| Water SCHEMBL9116894 | 0.79 | CA1 (0.60) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5016602 | 0.79 | CA1 (0.60) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL2526750 | 0.79 | CA1 (0.60) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL2524037 | 0.79 | CA1 (0.60) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11437017 | 0.79 | CA1 (0.60) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3769152 | 0.79 | CA1 (0.60) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675480-B1 | METHODS OF PREPARATION OF CONJUGATES | IMMUNOGEN INC (US) | 2018-12-26 | — | — | EP | claimed |
| US-20150344591-A1 | Sialic Acid Derivatives | LIPOXEN TECHNOLOGIES LIMITED (US) | 2015-12-03 | — | — | US | claimed |
| EP-2478049-B1 | A POLYMER SUPPORT | UNIV CAPE TOWN (ZA) | 2015-02-25 | — | — | EP | claimed |
| US-8293888-B2 | Sialic acid derivatives | LIPOXEN TECHNOLOGIES LIMITED (GB) | 2012-10-23 | — | — | US | claimed |
| EP-3337816-A1 | ALBUMIN VARIANTS AND CONJUGATES | Albumedix A/S (DK) | 2018-06-27 | — | — | EP | disclosed |
| WO-2017029407-A1 | ALBUMIN VARIANTS AND CONJUGATES | ALBUMEDIX A/S (DK) | 2017-02-23 | — | — | WO | disclosed |
| CN-104093425-A | Use of N-hydroxysuccinimide for improving the stability of conjugates | IMMUNOGEN INC | 2014-10-08 | — | — | CN | disclosed |
| US-8293888-B2 | Sialic acid derivatives | LIPOXEN TECHNOLOGIES LIMITED (GB) | 2012-10-23 | — | — | US | disclosed |
| US-20060147991-A1 | DNA chip and reactive solid carrier | FUJI PHOTO FILM CO., LTD. | 2006-07-06 | — | — | US | disclosed |
| US-20030096257-A1 | DNA chip and reactive solid carrier | FUJI PHOTO FILM CO., LTD. (JP) | 2003-05-22 | — | — | US | disclosed |
| US-20010008765-A1 | DNA chip and reactive solid carrier | FUJI PHOTO FILM CO., LTD. | 2001-07-19 | — | — | US | disclosed |
| EP-1106603-A2 | DNA chip and reactive solid carrier | FUJI PHOTO FILM CO., LTD. (JP) | 2001-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344591-A1 | Sialic Acid Derivatives | NEU2, NEU4, NEU1 | CA1 518/4885CA2 884/4885MMP1 2529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.