Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6045483 | 0.98 | KDM4E (0.47) | KDM4EALDH1A1NPSR1ATMTDP1 | |
| SCHEMBL6045602 | 0.87 | KDM4E (0.46) | KDM4EALDH1A1NPSR1ATMTDP1 | |
| Oxalic Acid SCHEMBL6045529 | 0.86 | CYP2D6 (0.42) | ALDH1A1MAPK1 | |
| SCHEMBL6045518 | 0.85 | CHRM2 (0.47) | ALDH1A1GAAKMT2AMEN1PHGDH | |
| Oxalic Acid SCHEMBL6045577 | 0.84 | FAAH (0.42) | KDM4EALDH1A1NPSR1GAAKMT2A | |
| SCHEMBL6045585 | 0.84 | OPRL1 (0.41) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL6045421 | 0.84 | CYP2D6 (0.44) | ALDH1A1MAPK1 | |
| Oxalic Acid SCHEMBL6045612 | 0.83 | KDM4E (0.40) | KDM4EALDH1A1TDP1GAAKMT2A | |
| Oxalic Acid SCHEMBL6045737 | 0.83 | MEN1 (0.41) | KDM4EALDH1A1ATMKMT2AMEN1 | |
| Oxalic Acid SCHEMBL6045590 | 0.83 | CHRM2 (0.33) | KDM4EALDH1A1NPSR1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252797-A1 | Receptor regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-11-09 | — | — | US | disclosed |
| EP-1559428-A1 | RECEPTOR REGULATOR | Takeda Pharmaceutical Company Limited (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252797-A1 | Receptor regulator | NMUR1, NMUR2, NMBR | KDM4E 3254/4885ALDH1A1 4220/4885NPSR1 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.