Glucuronic Acid

SCHEMBL6046181

Nc1ccn([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)n1.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	P2RY2	P41231	9/20	0.60

▸	P2RY6	Q15077	13/20	0.58

▸	P2RY4	P51582	6/20	0.56

▸	ST6GAL1	P15907	1/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Demannose SCHEMBL2164715	0.91	P2RY2 (0.62)	P2RY2P2RY6P2RY4
Galactose SCHEMBL6046195	0.91	P2RY2 (0.62)	P2RY2P2RY6P2RY4
Cystetine Triphosphate SCHEMBL28518918	0.88	P2RY2 (0.61)	P2RY2P2RY6P2RY4
Cytarabine 5'-Phosphate SCHEMBL28833023	0.88	P2RY2 (0.60)	P2RY2P2RY6ST6GAL1
Cystetine Triphosphate SCHEMBL28511450	0.87	P2RY2 (0.59)	P2RY2P2RY6P2RY4
SCHEMBL12595472	0.87	P2RY2 (0.76)	P2RY2P2RY6P2RY4
SCHEMBL532547	0.87	P2RY2 (0.76)	P2RY2P2RY6P2RY4
SCHEMBL18785149	0.87	P2RY2 (0.76)	P2RY2P2RY6P2RY4
SCHEMBL154172	0.87	P2RY2 (0.76)	P2RY2P2RY6P2RY4
SCHEMBL39904	0.87	P2RY2 (0.76)	P2RY2P2RY6P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20060141463-A1	Method of detecting bone paget's disease	NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP)	2006-06-29	—	—	US	disclosed
EP-1559781-A1	METHOD OF DETECTING BONE PAGET'S DISEASE	National Institute of Advanced Industrial Science and Technology (JP)	2005-08-03	—	—	EP	disclosed