Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 16/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627693 | 1.00 | ADRB2 (0.53) | ADRB2ADRB1ADRB3DRD2CYP1A2 | |
| SCHEMBL3626078 | 1.00 | ADRB2 (0.53) | ADRB2ADRB1ADRB3DRD2CYP1A2 | |
| SCHEMBL3626067 | 1.00 | ADRB2 (0.53) | ADRB2ADRB1ADRB3DRD2CYP1A2 | |
| SCHEMBL3627697 | 1.00 | ADRB2 (0.53) | ADRB2ADRB1ADRB3DRD2CYP1A2 | |
| SCHEMBL3619508 | 0.87 | ADRB2 (0.41) | ADRB2ADRB1ADRB3DRD2CYP1A2 | |
| SCHEMBL5584105 | 0.87 | ADRB2 (0.41) | ADRB2ADRB1ADRB3DRD2CYP1A2 | |
| SCHEMBL3619519 | 0.87 | ADRB2 (0.41) | ADRB2ADRB1ADRB3DRD2CYP1A2 | |
| SCHEMBL3625042 | 0.87 | ADRB2 (0.50) | ADRB2ADRB1 | |
| SCHEMBL3625038 | 0.87 | ADRB2 (0.50) | ADRB2ADRB1 | |
| SCHEMBL4430362 | 0.79 | ADRB2 (0.80) | ADRB2ADRB1ADRB3DRD2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730103-A1 | FORMAMIDE DERIVATIVES USEFUL AS ADRENOCEPTOR | Pfizer Limited (GB) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005092840-A1 | FORMAMIDE DERIVATIVES USEFUL AS ADRENOCEPTOR | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | disclosed |