Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | IDO1 | P14902 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11574226 | 0.98 | IDO1 (0.58) | RAB9AIDO1MAPTAKR1C3NPC1 | |
| SCHEMBL2299040 | 0.88 | IDO1 (0.58) | RAB9AIDO1MAPTAKR1C3NPC1 | |
| SCHEMBL11161448 | 0.85 | IDO1 (0.54) | RAB9AIDO1MAPTAKR1C3ALDH1A1 | |
| SCHEMBL11161443 | 0.85 | IDO1 (0.54) | RAB9AIDO1MAPTAKR1C3ALDH1A1 | |
| SCHEMBL10402671 | 0.84 | IDO1 (0.53) | RAB9AIDO1MAPTAKR1C3ALDH1A1 | |
| SCHEMBL6395921 | 0.84 | IDO1 (0.53) | RAB9AIDO1MAPTAKR1C3ALDH1A1 | |
| SCHEMBL10500161 | 0.84 | DPP8 (0.58) | RAB9AIDO1MAPTAKR1C3DPP8 | |
| SCHEMBL11165857 | 0.84 | IDO1 (0.53) | RAB9AIDO1MAPTAKR1C3ALDH1A1 | |
| SCHEMBL7108760 | 0.83 | IDO1 (0.56) | RAB9AIDO1MAPTAKR1C3NPC1 | |
| SCHEMBL11069589 | 0.82 | IDO1 (0.51) | RAB9AIDO1MAPTAKR1C3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060281686-A1 | Aza-peptides | LABORATOIRES SERONO SA (CH) | 2006-12-14 | — | — | US | disclosed |
| CN-1124846-C | N, N' -bis (sulfonyl) hydrazines as antitumor agents | UNIV YALE (US) | 2003-10-22 | — | — | CN | disclosed |
| CN-1278169-A | N, N' -bis (sulfonyl) hydrazines as antitumor agents | UNIV YALE (US) | 2000-12-27 | — | — | CN | disclosed |
| US-4377591-A | CARBAPENICILLIN ANTIBIOTICS | SANKYO COMPANY, LIMITED (JP) | 1983-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281686-A1 | Aza-peptides | APP, APBA1, IAPP | RAB9A 3494/4885IDO1 3262/4885MAPT 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.