SCHEMBL6046927

SCHEMBL6046927

CCCCN1CCCC1.CCCCN1CCCC1.CCCCN1CCCC1.CCCCN1CCCC1.CCCCN1CCCC1.CCCCN1CCCC1.CCCCN1CCCC1.CCCCN1CCCC1.CCCCN1CCCC1.CCCCN1CCCC1.CCCCN1CCCC1.CCCCN1CCCC1.O=P(O)(O)F.O=P(O)(O)F.O=P(O)(O)F.O=P(O)(O)F.O=P(O)(O)F.O=P(O)(O)F

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 3/20 0.51
S1PR3 Q99500 3/20 0.51
S1PR5 Q9H228 3/20 0.51
S1PR4 O95977 1/20 0.46
HRH3 Q9Y5N1 2/20 0.43
CYP1A2 P05177 2/20 0.42
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MAPT P10636 1/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.39
GLB1 P16278 1/20 0.38
USP2 O75604 1/20 0.38
BCHE P06276 1/20 0.38
LMNA P02545 1/20 0.38
CHRM2 P08172 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6046928 0.92 S1PR1 (0.57) S1PR1S1PR3S1PR5S1PR4HRH3
SCHEMBL172368 0.82
SCHEMBL4914238 0.82
SCHEMBL28057560 0.82 HRH3 (0.60) S1PR1S1PR3S1PR5HRH3CYP1A2
Bicarbonate SCHEMBL28170484 0.81 SMN1; SMN2 (0.57) S1PR1S1PR3S1PR5HRH3CYP1A2
SCHEMBL6506788 0.80 HRH3 (0.65) HRH3CYP1A2MAPK1SMN1; SMN2MAPT
Bromide SCHEMBL2191354 0.80 HRH3 (0.57) HRH3CYP1A2MAPK1SMN1; SMN2MAPT
Hydrochloric Acid SCHEMBL557224 0.80 HRH3 (0.57) HRH3CYP1A2MAPK1SMN1; SMN2MAPT
SCHEMBL20733674 0.80 HRH3 (0.65) HRH3CYP1A2MAPK1SMN1; SMN2MAPT
SCHEMBL60452 0.80 HRH3 (0.65) HRH3CYP1A2MAPK1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1730157-A1 IONIC LIQUIDS COMPRISING FLUORALKYLTRIFFLUOROBORATE ANIONS MERCK PATENT GmbH (DE) 2006-12-13 EP disclosed
WO-2005105815-A1 IONIC LIQUIDS COMPRISING FLUORALKYLTRIFFLUOROBORATE ANIONS MERCK PATENT GMBH (DE) 2005-11-10 WO disclosed