SCHEMBL6046948

SCHEMBL6046948

[CH2]CC(CCC)OC(=O)C(=C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TSHR P16473 4/20 0.39
THRB P10828 1/20 0.36
CTSK P43235 1/20 0.33
PRKCA P17252 1/20 0.32
PRKCD Q05655 1/20 0.32
CHRM1 P11229 1/20 0.31
AKR1A1 P14550 1/20 0.31
CHRM3 P20309 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP3A4 P08684 1/20 0.30
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11863394 0.90 ALDH1A1 (0.46) ALDH1A1TSHRTHRBCTSKPRKCA
SCHEMBL28169510 0.89 TSHR (0.44) ALDH1A1TSHRTHRBCTSKPRKCA
SCHEMBL27957787 0.87 TSHR (0.47) ALDH1A1TSHR
SCHEMBL440084 0.86 ALDH1A1 (0.43) ALDH1A1TSHRTHRBCTSKPRKCA
SCHEMBL8191468 0.86 TSHR (0.50) TSHR
SCHEMBL11049715 0.85 ALDH1A1 (0.41) ALDH1A1TSHRTHRBCTSKPRKCA
SCHEMBL15751384 0.84 TSHR (0.41) ALDH1A1TSHRTHRB
SCHEMBL9327223 0.83 TSHR (0.42) ALDH1A1TSHRTHRBCTSKPRKCA
SCHEMBL1692337 0.83 TSHR (0.46) ALDH1A1TSHRTHRBCTSKPRKCA
SCHEMBL13896953 0.81 ALDH1A1 (0.39) ALDH1A1TSHRTHRBCTSKPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2738610-B1 Electrophotographic photosensitive member, method for producing electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KK (JP) 2016-02-03 EP disclosed
US-9034545-B2 Electrophotographic photosensitive member, method for producing electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-05-19 US disclosed
US-20140154617-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-06-05 US disclosed
EP-2738610-A1 Electrophotographic photosensitive member, method for producing electrophotographic photosensitive member, process cartridge and electrophotographic apparatus Canon Kabushiki Kaisha (JP) 2014-06-04 EP disclosed
EP-1279443-B1 Antireflective, mar-resistant multilayer laminate SHINETSU CHEMICAL CO (JP) 2006-08-30 EP disclosed
US-6846568-B2 Antireflective, mar-resistant multilayer laminate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-01-25 US disclosed
US-20030087102-A1 Antireflective, mar-resistant multilayer laminate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-05-08 US disclosed
EP-1279443-A2 Antireflective, mar-resistant multilayer laminate Shin-Etsu Chemical Co., Ltd. (JP) 2003-01-29 EP disclosed