SCHEMBL6046949

SCHEMBL6046949

[CH2]C(C)COC(=O)C(=C)C

nearest known ligand 0.72

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.72
THRB P10828 1/20 0.45
ALDH1A1 P00352 2/20 0.42
TDP1 Q9NUW8 2/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10966647 0.84 TSHR (0.68) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL24562 0.84 TSHR (1.00) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL3319370 0.84 TSHR (0.75) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL8966000 0.84 TSHR (0.75) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL10494078 0.83 TSHR (0.67) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL198125 0.82 TSHR (0.65) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL20001266 0.82 TSHR (0.72) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL9082422 0.82 TSHR (0.95) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL9695772 0.82 TSHR (0.72) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL19017 0.82 TSHR (0.72) TSHRTHRBALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107207877-B Coated pigments, method for the production and use thereof, coating agents and articles 埃卡特有限公司 2020-09-29 CN disclosed
CN-105980487-A Coated metal pigments, method for the production and the use thereof, coating agent and article 埃卡特有限公司 2016-09-28 CN disclosed
CN-101506431-B Silicone rubber composition for fabric coating and coated fabric DOW CORNING TORAY CO LTD 2012-11-07 CN disclosed
CN-101506431-A Silicone rubber composition for fabric coating and coated fabric DOW CORNING TORAY CO LTD (JP) 2009-08-12 CN disclosed
CN-101367964-A Organosilicon nano-capsule DEGUSSA (DE) 2009-02-18 CN disclosed
EP-1279443-B1 Antireflective, mar-resistant multilayer laminate SHINETSU CHEMICAL CO (JP) 2006-08-30 EP disclosed
US-6846568-B2 Antireflective, mar-resistant multilayer laminate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-01-25 US disclosed
US-20030087102-A1 Antireflective, mar-resistant multilayer laminate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-05-08 US disclosed
EP-1279443-A2 Antireflective, mar-resistant multilayer laminate Shin-Etsu Chemical Co., Ltd. (JP) 2003-01-29 EP disclosed
US-4100172-A ADHESIVES, PRIMERS, LUBRICANT ADDITIVES UNION CARBIDE CORPORATION (US) 1978-07-11 US disclosed