SCHEMBL198125

SCHEMBL198125

[CH2]C(O)COC(=O)C(=C)C

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.65
THRB P10828 1/20 0.45
ALDH1A1 P00352 2/20 0.42
TDP1 Q9NUW8 2/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10966647 0.84 TSHR (0.68) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL94906 0.84 TSHR (0.68) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL20854815 0.84 TSHR (0.68) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL631029 0.84 TSHR (0.68) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL2585229 0.84 TSHR (0.68) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL7673814 0.82 THRB (0.61) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL9695772 0.82 TSHR (0.72) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL19998240 0.82 TSHR (0.65) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL6046949 0.82 TSHR (0.72) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL19017 0.82 TSHR (0.72) TSHRTHRBALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 869 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109459914-B Photocurable resin composition and use thereof 常州强力先端电子材料有限公司 2021-07-13 CN claimed
CN-109790243-A Three block prepolymer and its purposes in silicone hydrogels 庄臣及庄臣视力保护公司 2019-05-21 CN claimed
EP-3013874-B1 ADDITIVE THAT IMPROVES ADHESION AND COATING COMPOUND CONTAINING THE SAME BYK CHEMIE GMBH (DE) 2016-12-14 EP claimed
CN-104185468-A One-pack dental adhesive KURARAY NORITAKE DENTAL INC 2014-12-03 CN claimed
US-20110255040-A1 LIQUID CRYSTAL DISPLAY PANEL AU OPTRONICS CORP. (TW) 2011-10-20 US claimed
US-7777033-B2 Monomer with anti-microbial character, polymer using the same, and manufacturing method thereof MICRO SCIENCE TECH CO., LTD. (KR) 2010-08-17 US claimed
US-20080188655-A1 Monomer With Anti-Microbial Character, Polymer Using The Same, And Manufacturing Method Thereof MICRO SCIENCE TECH CO., LTD. (KR) 2008-08-07 US claimed
EP-1610831-B1 COLOR-STABLE SUPERABSORBENT POLYMER COMPOSITION BASF AG (DE) 2006-08-30 EP claimed
JP-3781773-B2 2006-05-31 JP claimed
WO-2004051276-A1 MAGNETIC PARTICLES FOR SEPARATING MICROORGANISMS FROM TECHNICAL MEDIA HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-06-17 WO claimed
EP-0026339-A1 Radiation curable coating composition and process for coating a substrate therewith GAF CORPORATION (US) 1981-04-08 EP claimed
US-4260809-A Copolymerizable, ultraviolet light absorber 4-alkoxy-2'-acryloxy benzazines GAF CORPORATION (US) 1981-04-07 US claimed
US-4260768-A Copolymerizable, ultraviolet light absorber 2-(2H-benzotriazol-2-yl)-4-alkylphenol acrylic acid esters GAF CORPORATION (US) 1981-04-07 US claimed
US-4247714-A Copolymerizable, ultraviolet light absorber 4-acryloyloxybenzal-1-alkyl-1-phenylhydrazone GAF CORPORATION (US) 1981-01-27 US claimed
US-4233441-A Copolymerizable, ultraviolet light absorber 4-acryloxybenzal-3-alkyl-2 N-benzothiazoloazines GAF CORPORATION (US) 1980-11-11 US claimed
US-4218392-A Two-step method of making copolymerizable, ultraviolet light absorber _2-cyano-3,3-diphenylacryloxy) alkylene acrylic acid esters GAF CORPORATION (US) 1980-08-19 US claimed
US-4207253-A Method of making copolymerizable, ultraviolet light absorber (2-cyano-3,3-diphenylacryloxy) alkylene acrylic acid esters GAF CORPORATION (US) 1980-06-10 US claimed
US-4198520-A Nonionic monomeric emulsion stabilizers THE KENDALL COMPANY (US) 1980-04-15 US claimed
US-4178303-A (2-Cyano-3,3-diphenylacryloxy) alkylene acrylic acid esters GAF CORPORATION (US) 1979-12-11 US claimed
US-3960935-A Nonionic monomeric emulsion stabilizers THE KENDALL COMPANY (US) 1976-06-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080188655-A1 Monomer With Anti-Microbial Character, Polymer Using The Same, And Manufacturing Method Thereof PCNA, HSF1, TERB1 TSHR 4599/4885THRB 4632/4885ALDH1A1 2231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.