Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047365 | 0.92 | ADORA2A (0.72) | ADORA2AALDH1A1 | |
| SCHEMBL6047293 | 0.91 | ADORA2A (0.72) | ADORA2AALDH1A1 | |
| SCHEMBL6047220 | 0.91 | ADORA2A (0.72) | ADORA2AALDH1A1 | |
| SCHEMBL6047236 | 0.88 | ADORA2A (0.58) | ADORA2A | |
| SCHEMBL6047219 | 0.87 | ADORA2A (0.57) | ADORA2AALDH1A1RAB9A | |
| SCHEMBL6047235 | 0.86 | ADORA2A (0.56) | ADORA2A | |
| SCHEMBL6047388 | 0.84 | ADORA2A (0.55) | ADORA2A | |
| SCHEMBL6867712 | 0.84 | ADORA2A (0.84) | ADORA2AALDH1A1CYP1A2RAB9A | |
| SCHEMBL6047314 | 0.84 | ADORA2A (0.56) | ADORA2A | |
| SCHEMBL6047247 | 0.84 | ADORA2A (0.54) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058320-A1 | [1,2,4] Triazolo[1,5-c]pyrimidine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-03-16 | — | — | US | disclosed |
| EP-1544200-A1 | 1,2,4 -TRIAZOLO 1,5-c PYRIMIDINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2005-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058320-A1 | [1,2,4] Triazolo[1,5-c]pyrimidine derivatives | ADORA2A, ADORA1, ADORA3 | ADORA2A 1/4885ALDH1A1 360/4885CYP1A2 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.