Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.55 |
| ▸ | ADA | P00813 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047384 | 0.85 | NPC1 (0.54) | ADORA2AADORA1ADORA3ADORA2BNPC1 | |
| SCHEMBL6047211 | 0.83 | ADORA2A (0.55) | ADORA2AADORA1ADORA3ADORA2BKMT2A | |
| SCHEMBL6047319 | 0.82 | ADORA2A (0.60) | ADORA2AADORA1ADORA3ADORA2BADA | |
| Hydrochloric Acid SCHEMBL6047221 | 0.80 | ADORA2A (0.53) | ADORA2A | |
| SCHEMBL931112 | 0.79 | ADORA2A (0.81) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL6047332 | 0.78 | ADORA2A (0.64) | ADORA2AADORA1ADORA3ADORA2BADA | |
| SCHEMBL6047173 | 0.78 | ADORA2A (0.55) | ADORA2A | |
| SCHEMBL6047201 | 0.77 | ADORA2A (0.50) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL6047315 | 0.77 | ADORA2A (0.61) | ADORA2A | |
| SCHEMBL6047175 | 0.77 | ADORA2A (0.66) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058320-A1 | [1,2,4] Triazolo[1,5-c]pyrimidine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058320-A1 | [1,2,4] Triazolo[1,5-c]pyrimidine derivatives | ADORA2A, ADORA1, ADORA3 | ADORA2A 1/4885ADORA1 2/4885ADORA3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.