SCHEMBL6047499

SCHEMBL6047499

CCCCCCCCON1C(C)(C)CC(C(CCC)(C(=O)O)C2CC(C)(C)N(OCCCCCCCC)C(C)(C)C2)CC1(C)C

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 5/20 0.33
HCAR2 Q8TDS4 2/20 0.33
GBA2 Q9HCG7 1/20 0.32
CES2 O00748 1/20 0.31
NAAA Q02083 1/20 0.30
GBA1 P04062 1/20 0.30
S1PR1 P21453 5/20 0.30
S1PR3 Q99500 4/20 0.30
S1PR5 Q9H228 4/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14795049 0.95 EPHX2 (0.33) EPHX2HCAR2GBA2CES2NAAA
SCHEMBL28538099 0.95 EPHX2 (0.33) EPHX2HCAR2GBA2CES2NAAA
SCHEMBL3951980 0.90 PPARG (0.36) EPHX2
SCHEMBL994337 0.89 PPARG (0.39) EPHX2
SCHEMBL9737418 0.89 PPARG (0.39) EPHX2
SCHEMBL995729 0.89 PPARG (0.39) EPHX2
SCHEMBL995804 0.89 PPARG (0.39) EPHX2
SCHEMBL992967 0.89 PPARG (0.39) EPHX2
SCHEMBL39175 0.89 PPARG (0.39) EPHX2
SCHEMBL995960 0.89 PPARG (0.39) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8668850-B2 Flame-retarded foamed plastic compositions and shaped articles DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2014-03-11 US claimed
US-8668850-B2 Flame-retarded foamed plastic compositions and shaped articles DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2014-03-11 US disclosed
US-20060229372-A1 Flame-retarded foamed plastic compositions and shaped articles DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2006-10-12 US disclosed