Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 10/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29189123 | 1.00 | FDPS (0.46) | FDPSGGPS1TSHRTHRBSMPD1 | |
| SCHEMBL11432930 | 1.00 | FDPS (0.46) | FDPSGGPS1TSHRTHRBSMPD1 | |
| SCHEMBL28036795 | 1.00 | FDPS (0.46) | FDPSGGPS1TSHRTHRBSMPD1 | |
| SCHEMBL9650717 | 0.97 | — | — | |
| SCHEMBL11442316 | 0.89 | — | — | |
| SCHEMBL7129095 | 0.81 | FDPS (0.48) | FDPSGGPS1TSHRTHRBSMPD1 | |
| SCHEMBL2707317 | 0.81 | FDPS (0.48) | FDPSGGPS1TSHRTHRBSMPD1 | |
| SCHEMBL1685841 | 0.81 | FDPS (0.48) | FDPSGGPS1TSHRTHRBSMPD1 | |
| SCHEMBL4633334 | 0.81 | FDPS (0.48) | FDPSGGPS1TSHRTHRBSMPD1 | |
| SCHEMBL28746873 | 0.81 | FDPS (0.48) | FDPSGGPS1TSHRTHRBSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074387-B2 | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SCHERING AG (DE) | 2006-07-11 | — | — | US | claimed |
| US-4188403-A | Cyclopentan-1-amines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-02-12 | — | — | US | disclosed |
| US-3932487-A | HYPOTENSIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-13 | — | — | US | disclosed |