Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.77 |
| ▸ | PPARD | Q03181 | 9/20 | 0.77 |
| ▸ | PPARA | Q07869 | 9/20 | 0.77 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.77 |
| ▸ | FABP4 | P15090 | 4/20 | 0.77 |
| ▸ | TERT | O14746 | 3/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | BLM | P54132 | 2/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.77 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | GMNN | O75496 | 1/20 | 0.77 |
| ▸ | USP2 | O75604 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | APEX1 | P27695 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27699499 | 1.00 | PPARG (0.77) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL11657049 | 1.00 | PPARG (0.77) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL7779886 | 1.00 | PPARG (0.77) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL28215391 | 1.00 | PPARG (0.77) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL7784335 | 0.98 | PPARG (0.73) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL27879390 | 0.96 | TOP1 (0.74) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL15367506 | 0.96 | F7 (0.77) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL7786847 | 0.93 | TOP1 (0.70) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL2718539 | 0.91 | PPARG (0.64) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL297328 | 0.91 | PPARG (0.64) | PPARGPPARDPPARAPTPN1FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074387-B2 | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SCHERING AG (DE) | 2006-07-11 | — | — | US | claimed |
| US-20030202943-A1 | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-30 | — | — | US | claimed |
| US-6565830-B1 | Contrast agent for imaging | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-05-20 | — | — | US | claimed |
| US-6287538-B1 | CONTRAST AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-09-11 | — | — | US | claimed |
| US-5859214-A | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SCHERING AKTIENGESELLSHAFT (DE) | 1999-01-12 | — | — | US | claimed |
| US-5843399-A | DTPA monoamides for MRI | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | claimed |
| EP-0450742-B1 | DTPA-Monoamids, pharmaceutical compositions containing them, their use and process for their preparation | SCHERING AG (DE) | 1994-07-06 | — | — | EP | claimed |
| EP-0450742-A1 | DTPA-Monoamids, pharmaceutical compositions containing them, their use and process for their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | claimed |
| US-7074387-B2 | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SCHERING AG (DE) | 2006-07-11 | — | — | US | disclosed |
| CN-1732039-A | dispersing or solubilizing agent containing calixarene compound | AJINOMOTO KK (JP) | 2006-02-08 | — | — | CN | disclosed |
| US-20050240051-A1 | Dispersing agent or solubilizing agent containing calixarene compound | AJINOMOTO CO., INC. (JP) | 2005-10-27 | — | — | US | disclosed |
| US-20030202943-A1 | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-30 | — | — | US | disclosed |
| US-6565830-B1 | Contrast agent for imaging | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-05-20 | — | — | US | disclosed |
| US-6287538-B1 | CONTRAST AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-09-11 | — | — | US | disclosed |
| US-5859214-A | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SCHERING AKTIENGESELLSHAFT (DE) | 1999-01-12 | — | — | US | disclosed |
| US-5843399-A | DTPA monoamides for MRI | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |
| EP-0450742-B1 | DTPA-Monoamids, pharmaceutical compositions containing them, their use and process for their preparation | SCHERING AG (DE) | 1994-07-06 | — | — | EP | disclosed |
| EP-0450742-A1 | DTPA-Monoamids, pharmaceutical compositions containing them, their use and process for their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030202943-A1 | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SLC43A1, HRH4, ACSL6 | PPARG 2228/4885PPARD 3719/4885PPARA 2731/4885 |
| US-20050240051-A1 | Dispersing agent or solubilizing agent containing calixarene compound | CALU, CALD1, CALR | PPARG 1492/4885PPARD 1202/4885PPARA 1287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.