Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 1.00 |
| ▸ | DRD3 | P35462 | 10/20 | 1.00 |
| ▸ | DRD4 | P21917 | 5/20 | 1.00 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454456 | 1.00 | DRD2 (1.00) | DRD2DRD3DRD4MTNR1AMTNR1B | |
| SCHEMBL29802351 | 1.00 | DRD2 (1.00) | DRD2DRD3DRD4MTNR1AMTNR1B | |
| SCHEMBL12072682 | 1.00 | DRD2 (1.00) | DRD2DRD3DRD4MTNR1AMTNR1B | |
| SCHEMBL1938120 | 1.00 | DRD2 (1.00) | DRD2DRD3DRD4MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL30485906 | 0.99 | DRD2 (0.97) | DRD2DRD3DRD4MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL29067180 | 0.99 | DRD2 (0.97) | DRD2DRD3DRD4MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL7445542 | 0.99 | DRD2 (0.97) | DRD2DRD3DRD4MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL30335264 | 0.99 | DRD2 (0.97) | DRD2DRD3DRD4MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL7450582 | 0.99 | DRD2 (0.97) | DRD2DRD3DRD4MTNR1AMTNR1B | |
| SCHEMBL15375766 | 0.92 | DRD2 (1.00) | DRD2DRD3DRD4MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113234057-B | Preparation method of rotigotine | 成都工业学院 | 2022-12-02 | — | — | CN | claimed |
| CN-113234057-A | Preparation method of rotigotine | 成都工业学院 | 2021-08-10 | — | — | CN | claimed |
| EP-2585428-B1 | PROCESSES FOR THE RESOLUTION OF NITROGEN SUBSTITUTED (S)-5-ALKOXY-2-AMINOTETRALIN DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2017-05-10 | — | — | EP | claimed |
| EP-2346811-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE (S)-(-)-2-(N-PROPYLAMINO)-5-METHOXYTETRALINE AND (S)-(-)-2-(N-PROPYLAMINO)-5-HYDROXYTETRALINE COMPOUNDS | INTERQUIM SA (ES) | 2012-08-15 | — | — | EP | claimed |
| US-20120041225-A1 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2012-02-16 | — | — | US | claimed |
| EP-1981831-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | Vaidya, Niteen A. (US) | 2008-10-22 | — | — | EP | claimed |
| WO-2007092264-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2007-08-16 | — | — | WO | claimed |
| US-20070185346-A1 | Kit for automated resolving agent selection and method thereof | VAIDYA NITEEN A | 2007-08-09 | — | — | US | claimed |
| WO-1991001957-A1 | RESOLUTION OF RACEMIC MIXTURES | ETHYL CORPORATION (US) | 1991-02-21 | — | — | WO | claimed |
| US-4968837-A | Resolution of racemic mixtures | ETHYL CORPORATION (US) | 1990-11-06 | — | — | US | claimed |
| US-4814477-A | SALT FORMATION, CRYSTALLIZATION, HYDROLYSIS | OCE-NEDERLAND B.V. (NL) | 1989-03-21 | — | — | US | claimed |
| US-20250304924-A1 | ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION OF KETONE AND AMINE COMPOUNDS | CODEXIS INC (US) | 2025-10-02 | — | — | US | disclosed |
| US-12312609-B2 | Engineered imine reductases and methods for the reductive amination of ketone and amine compounds | CODEXIS, INC. (US) | 2025-05-27 | — | — | US | disclosed |
| CN-117263843-A | Dopamine D 2 Receptor-like dual ligand compounds and uses thereof | 常州大学 | 2023-12-22 | — | — | CN | disclosed |
| CN-113234057-B | Preparation method of rotigotine | 成都工业学院 | 2022-12-02 | — | — | CN | disclosed |
| US-4564628-A | Substituted 2-aminotetralins | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1986-01-14 | — | — | US | disclosed |
| US-4465692-A | USING 2-(N-PHENYLETHYL-N-PROPYLAMINO)-5-HYDROXYTETRALIN | NELSON RESEARCH & DEVELOPMENT COMPANY (US) | 1984-08-14 | — | — | US | disclosed |
| US-4410519-A | 2-AMINO-5-HYDROXY DERIVATIVES | SANDOZ LTD. (CH) | 1983-10-18 | — | — | US | disclosed |
| EP-0026848-B1 | DERIVATIVES OF TETRALINE, THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS | SANDOZ AG (CH) | 1983-05-04 | — | — | EP | disclosed |
| EP-0026848-A1 | Derivatives of tetraline, their preparation and medicaments containing these compounds | SANDOZ AG (CH) | 1981-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041225-A1 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | ACKR3, KIT, C3AR1 | DRD2 1686/4885DRD3 1126/4885DRD4 276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.