Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909041 | 0.84 | ALDH1A1 (0.44) | TSHRKMT2AMEN1USP2POLB | |
| SCHEMBL6910415 | 0.84 | ALDH1A1 (0.44) | TSHRKMT2AMEN1USP2POLB | |
| SCHEMBL1775055 | 0.84 | ANTXR2 (0.41) | PAX8CA1CA2CA9ANTXR2 | |
| SCHEMBL1777390 | 0.84 | ANTXR2 (0.46) | PAX8CA1CA2CA9ANTXR2 | |
| SCHEMBL5802712 | 0.79 | TSHR (0.53) | TSHRPAX8PRKCAAKT1PTK2 | |
| SCHEMBL5802716 | 0.79 | TSHR (0.53) | TSHRPAX8PRKCAAKT1PTK2 | |
| SCHEMBL13617226 | 0.78 | TSHR (0.64) | TSHRPAX8PRKCAAKT1PTK2 | |
| SCHEMBL14429320 | 0.78 | TSHR (0.64) | TSHRPAX8PRKCAAKT1PTK2 | |
| SCHEMBL7150637 | 0.78 | TSHR (0.63) | TSHRPAX8PRKCAAKT1PTK2 | |
| SCHEMBL22866476 | 0.78 | TSHR (0.63) | TSHRPAX8PRKCAAKT1PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006055437-A2 | SYNTHESIS AND USE OF GLYCODENDRIMER REAGENTS | GENENCOR INTERNATIONAL, INC. (US) | 2006-05-26 | — | — | WO | disclosed |