SCHEMBL60481

SCHEMBL60481

O=C(O)c1cc(S)ccc1[N+](=O)[O-]

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DTYMK P23919 1/20 0.62
CASP6 P55212 1/20 0.50
TSHR P16473 3/20 0.46
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 2/20 0.42
LMNA P02545 1/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX15 P16050 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TTR P02766 1/20 0.42
PPOX P50336 1/20 0.42
AKR1B1 P15121 2/20 0.40
AKR1C4 P17516 2/20 0.40
AKR1C3 P42330 2/20 0.40
AKR1C2 P52895 2/20 0.40
AKR1C1 Q04828 2/20 0.40
AKR1B10 O60218 1/20 0.40
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29706389 1.00 DTYMK (0.62) DTYMKCASP6TSHRTDP1ALDH1A1
SCHEMBL4203103 0.85 DTYMK (0.49) DTYMKCASP6TSHRTDP1ALDH1A1
SCHEMBL23096734 0.85 DTYMK (0.45) DTYMKCASP6TSHRTDP1ALDH1A1
SCHEMBL28713313 0.84 DTYMK (0.44) DTYMKCASP6TSHRTDP1ALDH1A1
SCHEMBL7058241 0.84 MAPT (0.47) DTYMKCASP6TSHRTDP1ALDH1A1
SCHEMBL12025936 0.83 DTYMK (0.42) DTYMKCASP6TSHRTDP1ALDH1A1
SCHEMBL8582179 0.82 DTYMK (0.46) DTYMKCASP6TSHRTDP1ALDH1A1
SCHEMBL7864596 0.82 DTYMK (0.42) DTYMKCASP6TSHRTDP1ALDH1A1
SCHEMBL8187975 0.81 DTYMK (0.62) DTYMKCASP6TSHRTDP1ALDH1A1
SCHEMBL27586658 0.81 DTYMK (0.41) DTYMKCASP6TSHRTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5039 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12270821-B2 Device and method for assessing oxidative potential of ambient particulate matter THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2025-04-08 US claimed
CN-118190841-B Method for measuring consumption of DTT by PM2.5 南京信息工程大学 2024-10-25 CN claimed
US-12121588-B2 Large scale production process for capped and un-capped antibody cysteines and their use in therapeutic protein conjugation PFIZER INC. (US) 2024-10-22 US claimed
EP-3859804-B1 SEMICONDUCTOR DEVICE HAVING QUANTUM DOTS CANON KK (JP) 2024-08-07 EP claimed
CN-118190841-A Method for measuring consumption of DTT by PM2.5 南京信息工程大学 2024-06-14 CN claimed
CN-114250220-B Preparation and application of dopamine-coated sea urchin-shaped manganese dioxide hollow microspheres 中国科学院兰州化学物理研究所 2023-11-03 CN claimed
CN-116625966-A Method for analyzing correlation of flavonoid, anthocyanin and total phenol content of raspberry plant based on antioxidant capacity 江苏省中国科学院植物研究所 2023-08-22 CN claimed
US-20230158016-A1 DELTA OPIOID RECEPTOR ANTAGONISTS REPROGRAM IMMUNOSUPPRESSIVE MICROENVIRONMENT TO BOOST IMMUNOTHERAPY NATIONAL INSTITUTES OF HEALTH 2023-05-25 US claimed
US-11632995-B1 Methods of assembling apparel products having disulfide adhesives CREATEME TECHNOLOGIES INC. 2023-04-25 US claimed
EP-4107530-A1 PEPTIDE AND PROTEIN C-TERMINUS LABELING Board of Regents, The University of Texas System (US) 2022-12-28 EP claimed
EP-0567536-B1 METHOD FOR DIAGNOSING CELLULAR AGING OR INFLAMMATION CONDITION OF KERATINOCYTES, AND KIT FOR IMPLEMENTING SUCH METHOD OREAL (FR) 1995-03-22 EP claimed
US-5334384-A Treating the protein mixture with reducing agent to reduce disulfide bridge to free thiol group, which reacts with a reagent, separating modified protein impurity by filtration, sedimentation, centrifuging or retention within chromatography BEECHAM GROUP P.L.C. (GB) 1994-08-02 US claimed
EP-0365278-B1 Protein purification process BEECHAM GROUP PLC (GB) 1994-03-30 EP claimed
US-5094957-A In aqueous systems ROHM AND HAAS COMPANY (US) 1992-03-10 US claimed
EP-0365278-A2 Protein purification process BEECHAM GROUP PLC (GB) 1990-04-25 EP claimed
US-4654298-A Method for detection of peritoneal inflammation or infection ABBOTT LABORATORIES (US) 1987-03-31 US claimed
EP-0040506-B1 REACTIVE POLYMER AND PROCESS FOR THE PREPARATION THEREOF TEIJIN LIMITED (JP) 1986-08-20 EP claimed
EP-0178501-A1 Method for detection of peritoneal inflammation or infection ABBOTT LABORATORIES (US) 1986-04-23 EP claimed
US-4385169-A Reactive alpha amino acid polymer TEIJIN LIMITED (JP) 1983-05-24 US claimed
EP-0040506-A2 Reactive polymer and process for the preparation thereof TEIJIN LIMITED (JP) 1981-11-25 EP claimed