Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 15/20 | 0.47 |
| ▸ | DAGLA | Q9Y4D2 | 13/20 | 0.47 |
| ▸ | CES1 | P23141 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967780 | 0.83 | FAAH (0.58) | FAAHDAGLACES1 | |
| SCHEMBL13662362 | 0.83 | FAAH (0.58) | FAAHDAGLACES1 | |
| SCHEMBL5605374 | 0.80 | FAAH (0.41) | FAAHDAGLACES1NPC1RAB9A | |
| SCHEMBL6920576 | 0.79 | NPC1 (0.44) | FAAHDAGLACES1NPC1RAB9A | |
| SCHEMBL6208195 | 0.77 | DAGLA (0.40) | FAAHDAGLACES1NPC1RAB9A | |
| SCHEMBL3968583 | 0.76 | FAAH (0.63) | FAAHDAGLACES1 | |
| SCHEMBL13662364 | 0.76 | FAAH (0.63) | FAAHDAGLACES1 | |
| SCHEMBL4718852 | 0.76 | FAAH (0.41) | FAAHDAGLACES1NPC1RAB9A | |
| SCHEMBL4718848 | 0.76 | FAAH (0.41) | FAAHDAGLACES1NPC1RAB9A | |
| SCHEMBL5703655 | 0.76 | MAPT (0.70) | FAAHDAGLACES1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716158-A2 | SILINANE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | Schering Aktiengesellschaft (DE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005074904-A2 | SILINANE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | disclosed |