SCHEMBL6048271

SCHEMBL6048271

C=C(C)C(=O)NCCCN(Cl)C(C)=O

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.41
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
PAOX Q6QHF9 3/20 0.32
LMNA P02545 1/20 0.31
DNM1 Q05193 1/20 0.30
TGFBR1 P36897 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16908423 0.81 KDM4E (0.41) KDM4EMAPK1HIF1APAOXLMNA
Chloromethane SCHEMBL1655207 0.80 KDM4E (0.53) KDM4EPAOXLMNADNM1ALOX15
Chloromethane SCHEMBL8844942 0.80 KDM4E (0.53) KDM4EPAOXLMNADNM1ALOX15
SCHEMBL21954 0.79 KDM4E (0.56) KDM4EPAOXLMNADNM1ALOX15
SCHEMBL16798780 0.79 KDM4E (0.37) KDM4EMAPK1HIF1AL3MBTL1LMNA
SCHEMBL907569 0.78 KDM4E (0.52) KDM4EMAPK1HIF1APAOXTGFBR1
SCHEMBL632876 0.78 KDM4E (0.46) KDM4EMAPK1HIF1APAOXTGFBR1
Ammonia Solution, Strong SCHEMBL23532663 0.78 KDM4E (0.54) KDM4EPAOXLMNADNM1ALOX15
SCHEMBL18331463 0.78 KDM4E (0.42) KDM4EMAPK1HIF1APAOXLMNA
Hydrochloric Acid SCHEMBL111099 0.78 KDM4E (0.54) KDM4EPAOXLMNADNM1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060257560-A1 Polymer surfaces for insitu synthesis of polymer arrays AFFYMETRIX, INC. (US) 2006-11-16 US disclosed
EP-0419652-A1 POLYMERIC ELECTROPHORESIS MEDIA. EASTMAN KODAK CO (US) 1991-04-03 EP disclosed
WO-1990012820-A1 POLYMERIC ELECTROPHORESIS MEDIA EASTMAN KODAK COMPANY (US) 1990-11-01 WO disclosed