Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16309325 | 0.97 | KDM4E (0.44) | KDM4EMAPK1HIF1ATGFBR1MEN1 | |
| SCHEMBL907569 | 0.95 | KDM4E (0.52) | KDM4EMAPK1HIF1ATGFBR1MEN1 | |
| SCHEMBL24099895 | 0.93 | KDM4E (0.41) | KDM4EMAPK1HIF1ATGFBR1MEN1 | |
| SCHEMBL20319875 | 0.93 | KDM4E (0.58) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL59429 | 0.92 | KDM4E (0.56) | KDM4EMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL8775294 | 0.92 | KDM4E (0.56) | KDM4EMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL8775285 | 0.92 | KDM4E (0.56) | KDM4EMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL8775297 | 0.92 | KDM4E (0.56) | KDM4EMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL8775499 | 0.92 | KDM4E (0.56) | KDM4EMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL8774992 | 0.92 | KDM4E (0.56) | KDM4EMAPK1HIF1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250017827-A1 | Acid-Stable Glass Fillers And Self-Adhesive Dental Composite Cements With Good Transparency Containing Them | IVOCLAR VIVADENT AG (LI) | 2025-01-16 | — | — | US | claimed |
| EP-4488243-A1 | ACID-STABLE GLASS FILLERS AND SELF-ADHESIVE DENTAL COMPOSITE CEMENTS CONTAINING SAME HAVING GOOD TRANSPARENCY | Ivoclar Vivadent AG (LI) | 2025-01-08 | — | — | EP | claimed |
| US-20240158614-A1 | STORAGE STABLE SELF-ADHESIVE COMPOSITE CEMENTS WITH GOOD TRANSPARENCY AND GOOD RADIOPACITY | IVOCLAR VIVADENT AG (LI) | 2024-05-16 | — | — | US | claimed |
| EP-4356893-A1 | STORAGE STABLE SELF-ADHESIVE COMPOSITE CEMENTS WITH GOOD TRANSPARENCY AND GOOD RADIOPACITY | Ivoclar Vivadent AG (LI) | 2024-04-24 | — | — | EP | claimed |
| CN-117917236-A | Storage-stable self-adhesive composite cements with good transparency and good radiopacity | 义获嘉伟瓦登特公司 | 2024-04-23 | — | — | CN | claimed |
| EP-4205722-A1 | SELF-ADHESIVE DENTAL COMPOSITE WITH GOOD TRANSPARENCY | Ivoclar Vivadent AG (LI) | 2023-07-05 | — | — | EP | claimed |
| EP-4205723-A1 | HIGH TRANSPARENCY, SULPHATE-CONTAINING OR PHOSPHATE-CONTAINING DENTAL SELF-ADHERING COMPOSITE | Ivoclar Vivadent AG (LI) | 2023-07-05 | — | — | EP | claimed |
| EP-4205724-A1 | SELF-ADHESIVE DENTAL COMPOSITE CEMENTS WITH GOOD TRANSPARENCY BASED ON ACID-TREATED FILLERS | Ivoclar Vivadent AG (LI) | 2023-07-05 | — | — | EP | claimed |
| CN-116350520-A | Self-adhesive dental composite cement with good transparency based on acid treated fillers | 义获嘉伟瓦登特公司 | 2023-06-30 | — | — | CN | claimed |
| CN-116350518-A | Self-adhesive dental composite cement with good transparency | 义获嘉伟瓦登特公司 | 2023-06-30 | — | — | CN | claimed |
| US-20060178469-A1 | Polymerizable cyclopropyl acrylates | IVOCLAR VIVADENT AG | 2006-08-10 | — | — | US | claimed |
| EP-1688125-A1 | Polymerisable cyclopropylacrylates | Ivoclar Vivadent AG (LI) | 2006-08-09 | — | — | EP | claimed |
| EP-1674066-A1 | Self-etching dental materials based on (meth)acrylamidophosphates | Ivoclar Vivadent AG (LI) | 2006-06-28 | — | — | EP | claimed |
| US-20060135719-A1 | Self-etching dental materials based on (METH) acrylamide phosphates | IVOCLAR VIVADENT AG (LI) | 2006-06-22 | — | — | US | claimed |
| EP-1374829-B1 | Dental material on the basis of acryloester phosphonic acid | IVOCLAR VIVADENT AG (LI) | 2005-11-02 | — | — | EP | claimed |
| US-6900251-B2 | Dental materials based on acrylic-ester phosphonic acids | IVOCLAR VIVADENT AG (LI) | 2005-05-31 | — | — | US | claimed |
| EP-1413569-A1 | Bicyclic cyclopropane derivatives capable of polymerisation and their use in the preparation of dental materials | Ivoclar Vivadent AG (LI) | 2004-04-28 | — | — | EP | claimed |
| US-20040077882-A1 | Polymerizable bicyclic cyclopropane derivatives and their use for the preparation of dental materials | IVOCLAR VIVADENT AG (LI) | 2004-04-22 | — | — | US | claimed |
| US-20040077754-A1 | Dental materials based on acrylic-ester phosphonic acids | IVOCLAR VIVADENT AG (LI) | 2004-04-22 | — | — | US | claimed |
| EP-1374829-A1 | Dental material on the basis of acryloester phosphonic acid | Ivoclar Vivadent AG (LI) | 2004-01-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077882-A1 | Polymerizable bicyclic cyclopropane derivatives and their use for the preparation of dental materials | SCO2, CBR1, CORO1C | KDM4E 3685/4885MAPK1 2089/4885HIF1A 1454/4885 |
| US-20040077754-A1 | Dental materials based on acrylic-ester phosphonic acids | PHOSPHO1, RER1, PTGER1 | KDM4E 4283/4885MAPK1 202/4885HIF1A 496/4885 |
| US-20060178469-A1 | Polymerizable cyclopropyl acrylates | CBR3, CBR1, ACAD9 | KDM4E 3901/4885MAPK1 3326/4885HIF1A 2064/4885 |
| US-20250017827-A1 | Acid-Stable Glass Fillers And Self-Adhesive Dental Composite Cements With Good Transparency Containing Them | HAO2, HAO1, CDH1 | KDM4E 2828/4885MAPK1 1508/4885HIF1A 1618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.