Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 7/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272449 | 0.80 | TSHR (0.52) | TSHRMAOBCYP19A1ARKDM4E | |
| SCHEMBL15396044 | 0.80 | TSHR (0.52) | TSHRMAOBCYP19A1ARKDM4E | |
| SCHEMBL5162162 | 0.72 | TSHR (0.64) | TSHRMAOBCYP19A1ARKDM4E | |
| SCHEMBL27477390 | 0.71 | GAA (0.48) | TSHRCYP19A1GAAMAPTTAAR1 | |
| SCHEMBL2232707 | 0.70 | TSHR (0.41) | TSHRMAOBCYP19A1ARKDM4E | |
| Water SCHEMBL28096628 | 0.70 | TSHR (0.61) | TSHRMAOBCYP19A1ARKDM4E | |
| SCHEMBL29555382 | 0.70 | TSHR (0.61) | TSHRMAOBCYP19A1ARKDM4E | |
| SCHEMBL9417485 | 0.70 | TSHR (0.61) | TSHRMAOBCYP19A1ARKDM4E | |
| SCHEMBL29257507 | 0.69 | TSHR (0.59) | TSHRMAOBCYP19A1ARKDM4E | |
| SCHEMBL17053670 | 0.69 | LTA4H (0.38) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006028647-A1 | PROCESS FOR PRODUCING A WOLLASTONITE CONTAINING POLYESTER AND PRODUCTS AND ARTICLES PRODUCED THEREFROM | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-03-16 | — | — | WO | disclosed |