Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6525138 | 0.80 | PKM (0.41) | LMNA | |
| SCHEMBL5056659 | 0.80 | DPP4 (0.55) | DPP4KMT2APDCD1CD274BCAT2 | |
| SCHEMBL1547038 | 0.80 | KMT2A (0.56) | DPP4KMT2APDCD1CD274BCAT2 | |
| SCHEMBL15866832 | 0.80 | DPP4 (0.55) | DPP4KMT2APDCD1CD274BCAT2 | |
| SCHEMBL9271887 | 0.79 | DPP4 (0.54) | DPP4KMT2APDCD1CD274FOLH1 | |
| Hydrochloric Acid SCHEMBL27396597 | 0.78 | KMT2A (0.55) | DPP4KMT2APDCD1CD274BCAT2 | |
| SCHEMBL867318 | 0.77 | KMT2A (0.53) | DPP4KMT2APDCD1CD274BCAT2 | |
| SCHEMBL29358263 | 0.77 | KMT2A (0.53) | DPP4KMT2APDCD1CD274BCAT2 | |
| SCHEMBL6895317 | 0.76 | DPP4 (0.46) | DPP4KMT2APDCD1CD274FOLH1 | |
| SCHEMBL28173176 | 0.75 | DPP4 (0.54) | DPP4KMT2APDCD1CD274FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202953-B1 | SUBSTITUTED 2-DIALKYLAMINOALKYLBIPHENYL DERIVATIVES | GRUENENTHAL GMBH (DE) | 2006-08-30 | — | — | EP | claimed |