Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperidine SCHEMBL17338044 | 0.98 | APP (0.37) | APPEPHX2ALDH1A1MAPTTP53 | |
| Piperazine SCHEMBL29137239 | 0.91 | APP (0.41) | APPEPHX2ALDH1A1MAPTTP53 | |
| Piperidine SCHEMBL9509520 | 0.90 | EPHX2 (0.44) | EPHX2S1PR1GNAI3GNAO1GNAI1 | |
| Piperidine SCHEMBL4434690 | 0.85 | ALDH1A1 (0.39) | APPALDH1A1LMNATSHRMEN1 | |
| Morpholine SCHEMBL3318867 | 0.84 | MEN1 (0.41) | APPEPHX2ALDH1A1MAPTTP53 | |
| SCHEMBL31512497 | 0.82 | — | — | |
| SCHEMBL10012319 | 0.82 | — | — | |
| SCHEMBL5015 | 0.82 | — | — | |
| Piperidine SCHEMBL4297330 | 0.80 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2TSHRMEN1 | |
| Aziridine SCHEMBL29141899 | 0.80 | TSHR (0.43) | APPEPHX2ALDH1A1LMNAGNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006017898-A1 | ZWITTERIONIC ADDITIVES FOR ELECTROCHEMICAL DEVICES | MONASH UNIVERSITY (AU) | 2006-02-23 | — | — | WO | disclosed |