SCHEMBL6048872

SCHEMBL6048872

CCCCC[Si](Cl)(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
TSHR P16473 4/20 0.35
THRB P10828 1/20 0.35
ALDH1A1 P00352 1/20 0.33
EPHX1 P07099 1/20 0.32
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6048770 0.97 LMNA (0.41) LMNATSHRTHRBALDH1A1EPHX1
SCHEMBL6048778 0.97 LMNA (0.41) LMNATSHRTHRBALDH1A1EPHX1
SCHEMBL30001306 0.97 LMNA (0.41) LMNATSHRTHRBALDH1A1EPHX1
SCHEMBL6048812 0.97 LMNA (0.41) LMNATSHRTHRBALDH1A1EPHX1
SCHEMBL6048761 0.92 LMNA (0.34) LMNATSHRTHRBTDP1
SCHEMBL18108235 0.84 LMNA (0.36) LMNATSHRTHRBALDH1A1EPHX1
SCHEMBL18108059 0.84 LMNA (0.36) LMNATSHRTHRBALDH1A1EPHX1
SCHEMBL1223822 0.80
SCHEMBL12504535 0.79 LMNA (0.38) LMNATSHRTHRBALDH1A1EPHX1
SCHEMBL18107980 0.78 LMNA (0.31) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2658877-B1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORP (JP) 2023-04-12 EP disclosed
US-10023719-B2 Toughened polyolefin nanocomposites using silane functionalized polyolefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-07-17 US disclosed
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US disclosed
US-9499683-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2016-11-22 US disclosed
US-20160222187-A1 Toughened Polyolefin Nanocomposites Using Silane Functionalized Polyolefins EXXONMOBIL CHEMICAL PATENTS INC. 2016-08-04 US disclosed
US-20140031471-A1 Stabilization Of Polymers That Contain A Hydrolyzable Functionality BRIDGESTONE CORPORATION (JP) 2014-01-30 US disclosed
US-20130331520-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2013-12-12 US disclosed
CN-103391947-A Stabilization of polymers containing hydrolyzable functional groups BRIDGESTONE CORP 2013-11-13 CN disclosed
EP-2658877-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY Bridgestone Corporation (JP) 2013-11-06 EP disclosed
WO-2012092626-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2012-07-05 WO disclosed
US-7141634-B2 Catalyst for olefin polymerization and process for polymerizing olefins TOHO CATALYST CO., LTD. (JP) 2006-11-28 US disclosed
US-7005399-B2 Catalyst for polymerization of olefins TOHO TITANIUM CO., LTD. (JP) 2006-02-28 US disclosed
US-20050250918-A1 Catalyst for olefin polymerization and process for polymerizing olefins TOHO CATALYST CO., LTD. (JP) 2005-11-10 US disclosed
EP-1270604-A1 CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2003-01-02 EP disclosed
US-20020193244-A1 Catalyst for olefin polymerization TOHO TITANIUM CO., LTD. (JP) 2002-12-19 US disclosed