SCHEMBL6048898

SCHEMBL6048898

CCCCCC[Si](Br)(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
TSHR P16473 4/20 0.40
THRB P10828 1/20 0.40
EPHX1 P07099 1/20 0.35
ZDHHC7 Q9NXF8 1/20 0.32
DNM1 Q05193 5/20 0.32
ALDH1A1 P00352 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HSD17B10 Q99714 1/20 0.32
SLC22A1 O15245 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6048892 1.00 LMNA (0.41) LMNATSHRTHRBEPHX1ZDHHC7
SCHEMBL6048846 1.00 LMNA (0.41) LMNATSHRTHRBEPHX1ZDHHC7
SCHEMBL30001185 1.00 LMNA (0.41) LMNATSHRTHRBEPHX1ZDHHC7
SCHEMBL6048800 0.97 LMNA (0.38) LMNATSHRTHRBEPHX1
SCHEMBL6048713 0.90 LMNA (0.34) LMNATSHRTHRB
SCHEMBL18108109 0.87 LMNA (0.36) LMNATSHRTHRBEPHX1
SCHEMBL18108313 0.87 LMNA (0.36) LMNATSHRTHRBEPHX1
SCHEMBL18108170 0.80 LMNA (0.41) LMNATSHRTHRBEPHX1ZDHHC7
SCHEMBL18108085 0.80 LMNA (0.41) LMNATSHRTHRBEPHX1ZDHHC7
SCHEMBL18108177 0.80 LMNA (0.41) LMNATSHRTHRBEPHX1ZDHHC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022202119-A1 CURABLE COMPOSITION AND CURED OBJECT リンテック株式会社 2022-09-29 WO disclosed
US-9884928-B2 Polymers functionalized with activated nitrogen heterocycles containing a pendant functional group BRIDGESTONE CORPORATION (JP) 2018-02-06 US disclosed
US-20160289354-A1 POLYMERS FUNCTIONALIZED WITH ACTIVATED NITROGEN HETEROCYCLES CONTAINING A PENDANT FUNCTIONAL GROUP BRIDGESTONE CORPORATION (JP) 2016-10-06 US disclosed
US-7141634-B2 Catalyst for olefin polymerization and process for polymerizing olefins TOHO CATALYST CO., LTD. (JP) 2006-11-28 US disclosed
US-7005399-B2 Catalyst for polymerization of olefins TOHO TITANIUM CO., LTD. (JP) 2006-02-28 US disclosed
US-20050250918-A1 Catalyst for olefin polymerization and process for polymerizing olefins TOHO CATALYST CO., LTD. (JP) 2005-11-10 US disclosed
EP-1270604-A1 CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2003-01-02 EP disclosed
US-20020193244-A1 Catalyst for olefin polymerization TOHO TITANIUM CO., LTD. (JP) 2002-12-19 US disclosed