SCHEMBL6049038

SCHEMBL6049038

CCC(C)Oc1ccccc1-n1nnnc1C(C)C.CCCCOc1ccccc1-n1nnnc1C(C)C

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
MAPK1 P28482 2/20 0.38
KCNN4 O15554 6/20 0.36
TSHR P16473 4/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
NR1I2 O75469 1/20 0.35
P2RX7 Q99572 1/20 0.35
GAA P10253 1/20 0.35
MCHR1 Q99705 1/20 0.34
CASP1 P29466 1/20 0.34
DRD2 P14416 1/20 0.34
DRD3 P35462 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4209113 0.92 ALDH1A1 (0.45) ALDH1A1MAPK1KCNN4TSHRKMT2A
SCHEMBL4215231 0.91 KCNN4 (0.42) ALDH1A1MAPK1KCNN4TSHRKMT2A
SCHEMBL4209298 0.86 ALDH1A1 (0.48) ALDH1A1MAPK1KCNN4TSHRKMT2A
SCHEMBL4210039 0.81 ALDH1A1 (0.56) ALDH1A1MAPK1KCNN4TSHRKMT2A
SCHEMBL4211686 0.78 KCNN4 (0.51) ALDH1A1MAPK1KCNN4NPSR1P2RX7
SCHEMBL4207402 0.77 KCNN4 (0.45) ALDH1A1MAPK1KCNN4NPSR1P2RX7
SCHEMBL4207470 0.77 ALDH1A1 (0.44) ALDH1A1MAPK1KCNN4TSHRKMT2A
SCHEMBL6049029 0.76 KCNN4 (0.42) ALDH1A1MAPK1KCNN4TSHRKMT2A
SCHEMBL4212131 0.76 KCNN4 (0.41) ALDH1A1MAPK1KCNN4TSHRNPSR1
SCHEMBL4208591 0.76 KCNN4 (0.43) ALDH1A1MAPK1KCNN4TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1650198-A1 ALKOXYTETRAZOL-1-YLBENZALDEHYDE COMPOUND AND PROCESS FOR PRODUCING THE SAME Toyo Kasei Kogyo Company Limited (JP) 2006-04-26 EP disclosed