Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3315890 | 0.86 | POLB (0.56) | TDP1TSHRPOLBGAASMN1; SMN2 | |
| Benzoic Acid SCHEMBL29045930 | 0.79 | APEX1 (0.59) | TSHRDAONAPRTGAAKMT2A | |
| SCHEMBL10739512 | 0.79 | POLB (0.54) | TDP1TSHRPOLBGAASMN1; SMN2 | |
| SCHEMBL60588 | 0.79 | POLB (0.54) | TDP1TSHRPOLBGAASMN1; SMN2 | |
| SCHEMBL174303 | 0.79 | POLB (0.54) | TDP1TSHRPOLBGAASMN1; SMN2 | |
| SCHEMBL31737192 | 0.79 | POLB (0.54) | TDP1TSHRPOLBGAASMN1; SMN2 | |
| SCHEMBL10739509 | 0.79 | POLB (0.54) | TDP1TSHRPOLBGAASMN1; SMN2 | |
| Benzoic Acid SCHEMBL5142456 | 0.79 | TSHR (0.93) | TDP1TSHRDAONAPRTPOLB | |
| SCHEMBL14433706 | 0.79 | POLB (0.54) | TDP1TSHRPOLBGAASMN1; SMN2 | |
| SCHEMBL445084 | 0.78 | POLB (0.47) | TDP1TSHRDAONAPRTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270696-B1 | Adhesive sheet for dicing | NITTO DENKO CORP (JP) | 2006-03-29 | — | — | EP | disclosed |